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Sexual function of patients under surveillance for bladder cancer
Authors:Madelon NM Van Der Aa  Milou D Bekker  Theo H Van Der Kwast  Marie‐Louise Essink‐Bot  Ewout W Steyerberg  Ellen C Zwarthoff  Fatma EF Sen  Henk W Elzevier
Institution:1. Departments of Pathology,;2. Urology and;3. Department of Urology, Leids University Medical Center, Leiden,;4. Department of Pathology, University Health Network, Toronto, Canada;5. Department of Social Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands, and;6. Public Health, Erasmus MC Rotterdam, Rotterdam,
Abstract:

OBJECTIVE

To describe the prevalence of sexual dysfunction and evaluate risk factors in patients just diagnosed with non‐muscle‐invasive bladder cancer (NMI UC), who have the prospect of an intensive surveillance scheme by cysto‐urethroscopy to detect tumour recurrences.

PATIENTS AND METHODS

We conducted a cross‐sectional survey on 150 patients just diagnosed with primary or recurrent NMI UC. Patients were participating in a randomized clinical multicentre trial (CEFuB), comparing two surveillance schemes. Patients were asked to complete questionnaires at study entry 3 months before the start of the study‐surveillance scheme (demographic characteristics, a validated visual analogue scale, and validated subset of questions on sexual function and performance derived from QLQ‐BLS‐24). The results were compared with those from an age‐and gender‐matched healthy population.

RESULTS

The response rate was 95% (142/150); 61% (87/142) of the respondents were sexually active in the previous 4 weeks after diagnosis, 66% (70/105) of men and 46% (17/37) of women. Although libido was not negatively affected, 54% (47/87) of the patients had a sexual dysfunction, and 23% (17/73) were afraid to inflict harm on their partner by sexual contact. Sexually active patients perceived a higher state of general health (P = 0.03).

CONCLUSIONS

The prevalence of sexual dysfunction in patients with NMI UC is very high (54%) compared with an age‐ and gender‐matched healthy population (20–45%). No predictors for sexual dysfunction were found. These patients and partners would benefit from proper sexual information in the outpatient clinic.
Keywords:urothelial cancer  surveillance  sexual function  non‐muscle‐invasive bladder cancer
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