海拉尔铁路工务系统职工接种森林脑炎疫苗免疫效果观察

目的为了解海拉尔铁路工务系统的线路工人接种森林脑炎疫苗后的免疫效果。方法随机抽取工务系统在林业区段作业的402名职工,于预防接种前和接种后三周进行静脉采血,采用酶联免疫法进行抗体检测。结果免疫接种后抗体阳性率为98.76%;免疫前连续接种5年者抗体阳性率高于连续接种3年者、未连续接种者和从未接种者;吸烟、饮酒等不良生活习惯并不影响注射疫苗后抗体的产生。结论长春生物制品研究所研制的这种新型地鼠肾纯化灭活疫苗（森泰保）具有较高的抗体阳转率,但接种疫苗后的抗体水平维持时间较短,需每年进行加强注射才能维持身体内的抗体水平。接种年限越长血清抗体水平越高。吸烟、饮酒不良生活习惯不影响抗体的产生。

Immunological Effect of Tick-bome encephalitis vaccine about worker of Hailar Railway construction system

Objective To understand the system works Hailar line railway workers after vaccination encephalitis vaccine immunogenicity.Methods Randomly selected 402 workers operating in the forestry section,gathering inoculation blood Before vaccination and after intravenous three weeks, Enzyme-linked immunosorbent assay for antibody detection.Results rate of Antibody is 98.76%after immunization;antibody positive rate of Continuous 5 years vaccination is higher than that of 3 years and vaccination is not continuous and never vaccinated;Smoking and drinking habits do not affect the production of antibodies after vaccination.Conclusion his new type of hamster kidney purified inactivated vaccine（Sentai Paul） developed by Changchun Institute of Biological has a high rate of seroconversion,However,antibody levels maintain shorter after vaccination,to maintain the body＇s antibody levels Needs annual booster shots.Longer inoculation period the higher the level of serum antibody.bad habits such as smoking,drinking ect,do not affect the production of antibodies.