| 131I治疗Graves病后暂发性甲低的临床分析 |
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| 引用本文： | 刘剑锋,方毅,张秀丽,叶根耀,邢家骝,张有仁,姚燕.131I治疗Graves病后暂发性甲低的临床分析[J].军事医学科学院院刊,2003,27(6):447-448. |
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| 作者姓名： | 刘剑锋 方毅 张秀丽 叶根耀 邢家骝 张有仁 姚燕 |
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| 作者单位： | 1. 军事医学科学院附属医院,北京,100039
2. 北京市冶金医院,北京,100029 |
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| 摘 要： | 目的：探讨^131I治疗后暂发性甲低的临床特点和转归。方法：对32例^131I治疗后出现暂发性甲低的患者进行临床分析和随访。结果：暂发性甲低出现在^131I治疗后2～6个月，有甲低症状者19例(59．38％)。甲低缓解后甲状腺功能正常者20例(62．5％)，又甲亢者12例(37．5％)。甲低时，T3和T4明显降低，TSH变化不一。结论：暂发性甲低多发生在低剂量^131I治疗的患者，甲低缓解后部分患者可再次出现甲亢。
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| 关 键 词： | 格雷夫斯病 甲状腺功能减退症 抗甲状腺药 |
| 文章编号： | 1000-5501(2003)06-0447-02 |
| 修稿时间： | 2003年2月18日 |
Transient hypothyroidism after 131I treatment of Graves disease |
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| LIU Jian-Feng ,FANG Yi ,ZHANG Xiu-Li ,YE Gen-Yao ,XING Jia-Liu ,ZHANG You-Ren ,YAO Yan.Transient hypothyroidism after 131I treatment of Graves disease[J].Bulletin of the Academy of Military Medical Sciences,2003,27(6):447-448. |
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| Authors: | LIU Jian-Feng FANG Yi ZHANG Xiu-Li YE Gen-Yao XING Jia-Liu ZHANG You-Ren YAO Yan |
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| Institution: | LIU Jian-Feng 1,FANG Yi 1,ZHANG Xiu-Li 1,YE Gen-Yao 1,XING Jia-Liu 1,ZHANG You-Ren 1,YAO Yan 2 |
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| Abstract: | Objective:To evaluate the results of the transient hypothyroidism after 131 I treatment of Graves disease.Methods:A total of 32 transient hypothyroidism patients treated with 131 I for Graves disease were studied and followed up. Results:Transient hypothyroidism occurred within 2-6 months after 131 I treatment and 19 patients were symptomatic. At diagnosis of transient hypothyroidism, T 3 and T 4 levels were decreased had normal, TSH levels were increased,normal or low. Follow-up examination found that 20 patients thyroid and 12 patients had relapse of hyperthyroidism.Conclusions:Therapy of Graves disease with low doses of 131 I causes a high incidence of transient hypothyroidism. After recovery of transient hypothyroidism, some patients have relapse of hyperthyroidism. |
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| Keywords: | Graves disease hypothyroidism antithyroid agents |
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