Cutaneous gamma/delta T‐cell lymphoma |
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| Authors: | Richard Koch Elaine S. Jaffe Christian Mensing Matthias Zeis Norbert Schmitz Christian A. Sander |
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| Affiliation: | 1. Eduard‐Arning Clinic for Dermatology and Allergology Asklepios Klinik St. Georg, Hamburg, Germany;2. Hematopathology Section, Laboratory of Pathology, NCI, Bethesda, USA;3. Department of Hematology, Asklepios Klinik St. Georg, Hamburg, Germany |
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| Abstract: | Only 40 cases of primary cutaneous gamma/delta T‐cell lymphoma (GD‐TCL) have been described. GD‐TCL was included as a provisional entity in the WHO‐EORTC classification of cutaneous lymphomas in 2005. GD‐TCL often failed to respond to polychemotherapy and radiation therapy and have a poor prognosis with a mean survival of only 15 months. We present a patient treated with surgery, immunomodulatory therapy, and polychemotherapy. He then received hematopoietic stem cell transplantation and has been in complete remission since. Allogeneic stem cell transplantation appears to be a promising therapeutic option for aggressive and generally fatal lymphomas like GD‐TCL. |
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| Keywords: | gamma/delta‐T‐cell‐receptor cutaneous lymphoma hematopoietic stem cell transplantation |
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