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Venous leg ulcers: patient concordance with compression therapy and its impact on healing and prevention of recurrence
Authors:Christine Moffatt  Dheerendra Kommala  Nathalie Dourdin  Yoonhee Choe
Affiliation:1. Christine Moffatt, PhD, Glasgow University Medical School, Glasgow, UK and Cardiff School of Medicine, Cardiff, UK;2. Dheerendra Kommala, MD, ConvaTec, Skillman, NJ, USA;3. Nathalie Dourdin, PhD, BioMedCom Consultants Inc., Montréal, Québec, Canada;4. Yoonhee Choe, PharmD, MHS, ConvaTec, Skillman, NJ, USA
Abstract:This study aimed to review available data on the reasons attributed to patient non concordance with compression therapy for the treatment of venous leg ulcers (VLUs), the frequency of non concordance and its effects on clinical outcomes. The biomedical literature was searched for publications on VLUs, compression therapy and concordance over the past 20 years. Physical, aesthetic and cosmetic factors, patient lack of education about VLUs, cost of therapy and issues with treatment by clinicians were all reported to influence concordance with compression therapy. The search identified 10 studies reporting patient concordance with compression stockings or bandages; while non concordance ranged from 2% to 42% of patients in three randomised controlled trials, it was generally higher in real‐world studies, ranging from 9.7% to 80%. Another set of six studies indicated that the healing rate was half and the median time to complete healing was twice as long when patients were not concordant. Further, recurrence rates were 2–20 times greater when patients did not comply with the use of stockings following VLU healing. In conclusion, published biomedical literature has documented that non concordance with compression therapy negatively impacts the outcome of VLUs, highlighting the need to improve patient concordance to maximise therapeutic benefits.
Keywords:Compression therapy  Concordance  Healing  Recurrence  Venous leg ulcers
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