肝转移瘤的适形放射治疗

目的观察适形放射治疗对肝转移瘤的治疗效果方法1997－09／1998－04我们采用立体定向适形放射治疗8例肝转移瘤（分别有1～5个转移灶），并进行了术后随访．肿瘤的临床靶体积（CTV）为0．6cm3～232cm3（平均36．4cm3），计划靶体积（PTV）最小照射量为每次照射3．96Gy～6．30Gy（平均5．08Gy），PTV最大照射量为每次照射5．63Gy～10．88Gy（平均6．84Gy），处方剂量（PD）为4．0Gy～6.5Gy（平均5．13Gy），分2～8次进行适形放射治疗．结果治疗过程中无1例死亡.患者一般状况的计分标准（KPS）：术前20～90分（平均58．8分），术后30～100分（平均71．2分）．实体瘤疗效标准：完全缓解（CR）：2例：部分缓解（PR）：3例；无变化（NC）：2例；进展（PD）：1例.在术后2mo～9mo随访期间，我们观察到87.5％的受照射肿瘤得到控制62．5％的肿瘤缩小或消失.结论立体定向适形放射治疗对肝转移瘤有良好的治疗效果.

Conformal radiotherapy of metastatic hepatic cancer

AIM To observe the therapeutic effect of conformal radiotherapy on metastatic hepatic cancer.METHODS From September 1997 to April 1998, 8 cases of metastatic hepetic cancer (1 to 5 metastatic focus respectively) were treated with stereotactic radiotherapy and underwent follow-up after the therapy. The clinical target volume (CTV) of tumor ranged from 0.6 cm3 to 232 cm3 (mean 36.4 cm3 ), the lowest irradiation dose of planning target volume (PTV) was 3. 96Gy-6. 30Gy each time (mean 5 .08Gy); the highest irradiation dose of PTV was 5.63Gy - 10.88Gy each time (mean 6.84Gy), the prescribed dose (PD) was 4Gy - 6 .5Gy each time (mean 5. 13Gy), 2 - 8 occasions totally.RESULTS No petient died during therapy. KPS of petients normal condition was 20 - 90 before treatment (mean 58,8 ), 30 -100 after treatment (mean 71 .2 ).Therapeutic effect standard of entity tumor: completely relaxed (CR) two cases, pertly relaxed (PR) three cases,no change (NC) two cases, progressed (PD) one case.During a follow-up period of 2 - 9 months, 87.5% of the tumors were controlled (no progressive disease). 62. 5%of the tumors decreased in size or disappeared.CONCLUSION Stereotactic radiotherapy has good therapeutic effects on metastatic hepetic cancer.