| HPLC法测定双藤痹痛凝胶膏剂中雷公藤甲素和青藤碱的含量 |
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| 引用本文： | 严国鸿,褚克丹,徐伟,李煌,夏裕发,方宇骅,陈立典.HPLC法测定双藤痹痛凝胶膏剂中雷公藤甲素和青藤碱的含量[J].福建中医学院学报,2013(5):27-30. |
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| 作者姓名： | 严国鸿 褚克丹 徐伟 李煌 夏裕发 方宇骅 陈立典 |
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| 作者单位： | 福建中医药大学附属人民医院;福建中医药大学药学院;福建中医药大学 |
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| 基金项目： | 福建省科技厅重大专项(2009YZ0001-1-1);十二·五国家科技支撑计划项目(2011BAI01B05) |
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| 摘 要： | 目的控制双藤痹痛凝胶膏剂的质量。方法用HPLC法测定双藤痹痛凝胶膏剂中雷公藤甲素和青藤碱的含量。结果雷公藤甲素的线性范围为1.5216~15.2160μg/mL,平均回收率为98.07%;青藤碱的线性范围为8.5524~85.5240μg/mL,平均回收率为98.32%。结论 HPLC法操作简便快速,结果准确,重现性好,可用于双藤痹痛凝胶膏剂的质量控制。
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| 关 键 词： | 双藤痹痛凝胶膏剂 雷公藤甲素 青藤碱 高效液相色谱法 |
Determination of Triptolide and Sinomenine in Shuangteng Bitong Cataplasm by HPLC |
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| Institution: | YAN Guohong;CHU Kedan;XU Wei;The First Affiliated Hospital,FUTCM;College of Pharmacy,FUTCM; |
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| Abstract: | Objective To control the quality of Shuangteng Bitong cataplasm.Methods The contents of Triptolide and Sinomenine in Shuangteng Bitong cataplasm were determined by HPLC.Results The linear range of Triptolide was 1.5216-15.2160 μg·mL-1,and the average recovery was 98.07%.The linear range of Sinomenine was 8.5524-85.5240 μg·mL-1,and the average recovery was 98.32%.Conclusion This method is simple,rapid,accurate,reproducible,and could be used for the quality control of Shuangteng Bitong cataplasm. |
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| Keywords: | Shuangteng Bitong cataplasm Triptolide Sinomenine HPLC |
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