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| 雾化烧伤灵药效学研究 | |
| 引用本文： | 唐可欣,王凤斌,马麦生,张卫华,单平秀,黄洋,冯立国. 雾化烧伤灵药效学研究[J]. 潍坊医学院学报, 2002, 24(3): 191-192 |
| 作者姓名： | 唐可欣 王凤斌 马麦生 张卫华 单平秀 黄洋 冯立国 |
| 作者单位： | 1. 潍坊医学院,山东,潍坊,261042 2. 潍坊市中医院 3. 高密市人民医院 |
| 基金项目： | 潍坊市科委资助课题 (课题号 :) |
| 摘 要： | 目的 观察雾化烧伤灵治疗烧伤的药理学作用并探讨其作用机制。方法 制作豚鼠浅Ⅱ度、深Ⅱ度烧伤模型及Ⅲ度烧伤感染模型 ,观察雾化烧伤灵组 (实验组 )、湿润烧伤膏组 (药物对照组 )及空白对照组 (溶剂组 )烧伤创面结痂面积、脱痂时间和愈合时间的变化。结果 与空白对照组比较 ,雾化烧伤灵组可明显减少创面渗出、缩小结痂面积、缩短脱痂时间及愈合时间 (P <0 .0 1) ,且其作用明显优于湿润烧伤膏组 (P <0 .0 5 ) ,并可抑制烧伤创面绿脓杆菌的感染。结论 雾化烧伤灵具有明显的促进烧伤创面愈合及创面抗感染作用 ,是一种较理想的外用治疗烧伤药物 |
| 关 键 词： | 烧伤 雾化烧伤灵 药效学 豚鼠 |
| 文章编号： | 1004-3101(2002)03-0191-02 |
| 修稿时间： | 2001-12-12 |
Study on Pharmacodynamics of Shaoshangling Spray |
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| TANG Ke xin,WANG Feng bin,MA Mai sheng,ZHANG Wei hua,SHAN Ping xiu,HUNAG Yang,FENG Li guo. Study on Pharmacodynamics of Shaoshangling Spray[J]. Journal of Weifang Medical College, 2002, 24(3): 191-192 | |
| Authors: | TANG Ke xin WANG Feng bin MA Mai sheng ZHANG Wei hua SHAN Ping xiu HUNAG Yang FENG Li guo |
| Abstract: | Objective To observe the pharmacology action of Shaoshangling Spray(SSLS) on treatment to burn and research it's effect mechanism.Method Make guineapig models of low and deep second degree burn and the third degree burn infection,observe scab area,decrustation and healing time changes of burn surface in treatment(SSLS) group,drug control (Moist Burn Ointment,MBO )group and no drug control(Solvent S.) group.Result Comparing with no drug control group,treatment group can apparently decrease burn surface exudation,scab area,decrustation and healing time(P<0.01),and the last two action were apparently better than MBO group(P<0.05),furthermore the SSLS group can inhibit infection of green pus bacillus to burn surface.Conclusion SSLS have obvious effects on promoting burn surface healing and anti infection.It is a perfect external drug to burn. |
| Keywords: | Burn Shaoshangling spray Pharmacodynamics Guineapig |
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