成年男性身体脂肪含量与肺通气功能及代谢指标的关系

目的：研究成年男性身体脂肪含量及分布与肺通气功能及代谢指标的关系。方法抽取来我院行健康体检男性600人，年龄22～77岁，进行调查问卷填写、人体成分分析、肺功能测定及血生化指标检测。分析体脂百分比（ percentage of body fat， PBF）、腰臀比（waist to hip ratio， WHR）与肺活量（vital capacity， VC）、用力呼气肺活量（force vital capacity，FVC）等肺通气功能指标的关系。结果20～45岁组PBF肥胖率、WHR肥胖率分别为70．68％、70．30％，低于45岁以上组（76．05％、81．74％），差异有统计学意义（P＜0．01）；PBF、WHR肥胖组与正常组相比，肺通气功能均明显下降；PBF与VC、FVC、FEV1、PEF呈负相关，与FEV1/FVC 呈正相关；WHR与VC、FVC、FEV1、PEF呈负相关。 WHR 与FPG、UA、TG、LDL-C呈正相关。结论成年男性PBF升高和中心性肥胖是肺通气功能下降损伤和代谢紊乱的危险因素。

Relationship between percentage body fat and lung ventilation function and metabolic index in adult males

Objective To investigate the effect of the body fat content and distribution on pulmonary ventilatory function and related metabolic index in the adult males .Methods Based on cluster sampling , we enrolled 600 healthy adult males aged 22-77 years in this hospital from November 2012 to April 2014.The basic data were obtained through the questionnaire survey .Finally we ex-amined the relationship between the percentage body fat （PBF）, waist-hip ratio（WHR） and VC,FVC,FEVl,FEV1/VC,FEV1/FVC, PEF,FPG,UA,TG,TC,HDL-C, LDL-C.Results WHR tended to increase along with age .PBF obesity rate and WHR obesity rate tended to increase with age .Compared with the normal group , the pulmonary ventilation function reduced significantly in PBF and WHR obesity group.There was a negative correlation between PBF and VC , FVC, FEV, PEF.But PBF showed an obvious positive correlation with FEV1 /FVC.PBF was positively associated with FPG , UA, TG, TC, HDL-C and LDL-C.WHR was positively corre-lated with FPG、UA、TG and LDL-C.Conclusions Increase in PBF and central obesity in adult males are the risk factors of pulmonary ventilation function impairment and metabolic disorders .