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老年期抑郁症的伴随性负变研究
引用本文:张载福,胡若笑,杨致蓉,范卫星,吕望强,朱建唯,姜小球,陈冲. 老年期抑郁症的伴随性负变研究[J]. 神经病学与神经康复学杂志, 2008, 5(3)
作者姓名:张载福  胡若笑  杨致蓉  范卫星  吕望强  朱建唯  姜小球  陈冲
作者单位:浙江省金华市第二医院老年精神科,金华,321016;上海交通大学医学院附属精神卫生中心神经生理室,上海,200030
基金项目:金华市科学技术局资助项目  
摘    要:目的 探讨老年期抑郁症患者的伴随性负变(CNV)变化特征.方法 应用美国Nicolet脑诱发电位仪,记录了21例老年期抑郁症患者的CNV,并与33例正常对照者和39例非老年期抑郁症患者的CNV进行比较.结果 老年期抑郁症患者的CNV变化与非老年期抑郁症患者的CNV变异基本类似,但CNV波幅降低更明显,PINV出现率更高,反应时间进一步延长.结论 CNV是评定老年期抑郁症患者大脑综合功能的有效工具.

关 键 词:老年期抑郁症  伴随性负变  正常老人

Study of Contingent Negative Variations in Senile Depression
Zhang Zaifu,Hu Ruoxiao,Yang Zhirong,Fan Weixing,Lu Wangqiang,Zhu Jianwei,Jiang Xiaoqiu,Chen Chong. Study of Contingent Negative Variations in Senile Depression[J]. Journal of Neurology and Neurorehabilitation, 2008, 5(3)
Authors:Zhang Zaifu  Hu Ruoxiao  Yang Zhirong  Fan Weixing  Lu Wangqiang  Zhu Jianwei  Jiang Xiaoqiu  Chen Chong
Affiliation:Zhang Zaifu1,Hu Ruoxiao1,Yang Zhirong1,Fan Weixing1,Lv Wangqiang1,Zhu Jianwei1,Jiang Xiaoqiu1,Chen Chong2(1Department of Senile Mental Disease,Jinhua City Second Hospital,Jinhua 321016,2Department of Electrophysiology,Mental Health Center affiliated to Medical School,Shanghai Jiaotong University,Shanghai 200030,China)
Abstract:Objective In order to investigate the changes of contingent negative variations (CNVs) in senile depressive patients, the present study was initiated. Methods An event-related potentials CNVs were recorded from 21 senile depressive patients by using a Nicolet Spirit Instrument, and were compared with those of 33 normal controls and 39 non-senile depressives. Results The CNV presentation of senile depression was similar to that of non-senile depression, but with a lower amplitude, a higher incidence of PINV ...
Keywords:senile depression  contingent negative variations  the normal elderly  
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