活血化瘀汤治疗神经根型颈椎病的临床研究

目的观察活血化瘀汤治疗神经根型颈椎病的临床疗效。方法将152例神经根型颈椎病,随机分为活血化瘀汤治疗组(87例)和颈复康颗粒对照组(65例),分别观察两组患者治疗前后主要症状疼痛程度(VAS法)、血液流变学指标、血清细胞因子IL-10和血黏附因子的变化,并比较两组疗效。结果治疗组和对照组治疗后疼痛积分较治疗前均明显减少(P<0.01),两组间治疗前后疼痛积分的差值比较,有显著性差异(P<0.05);血液流变学指标、血清细胞因子IL-10和血黏附因子,治疗后两组均有显著性差异(P<0.05);治疗组的治愈率、有效率与对照组比较有显著性差异(P<0.05)。结论活血化瘀汤治疗神经根型颈椎病有明显的疗效。

Clinical Study on Treatment of Medicinal Broth of Activate Blood Circulation for Nerve-root Cervical Spondylosis

Objective To observe the clinical therapeutic effect of medicinal broth of activate blood circulation on nerve-root cervical spondylosis.Methods A total of 152 patients with nerve-root cervical spondylosis were selected and divided into two groups: treatment group with medicinal broth of activate blood circulation(n=87) and control group with Jing Fu Kang(n=65).Pain degree(VAS method),hemorheological indexes,serum interleukin(IL)-10 and adhesion molecule were observed before and after treatment and the clinical therapeutic effect of the two groups were compared.Results Pain scores of the two groups were lower after treatment than before treatment(P<0.01),and the difference in pain scores of post-treatment between the two groups was obvious(P<0.05).Hemorheological indexes,IL-10 and adhesion molecule after treatment between the two groups were obviously different(P<0.05).The differences in cure rate and effective rate between the two groups were positive(P<0.05).Conclusion The treatment effect of medicinel broth of activate blood circulation is significant for nerve-root cervical spondylosis.