| 羚羊角脂类成分的提取与甲酯化条件优化 |
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| 引用本文： | 徐爱仁,胡晓炜,马卫成,应锦艳. 羚羊角脂类成分的提取与甲酯化条件优化[J]. 医药导报, 2011, 30(4): 433-436. DOI: 10.3870/yydb.2011.04.007 |
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| 作者姓名： | 徐爱仁 胡晓炜 马卫成 应锦艳 |
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| 作者单位： | 1. 浙江省宁波市泌尿肾病医院药剂科,315100
2. 杭州市药品检验所,310017 |
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| 基金项目： | 宁波市自然科学基金资助项目 |
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| 摘 要： | 目的 建立羚羊角脂类成分最佳提取与甲酯化方法. 方法对羚羊角中脂类成分提取与甲酯化条件进行筛选和优化,在选择合适的脂类提取方法和甲酯化方法基础上,分别考察提取时间对提取效率的影响及催化剂用量、反应温度、反应时间对甲酯化效果的影响. 结果 确定最佳提取方法为三氯甲烷 甲醇改良法,最佳甲酯化方法为硫酸甲醇法. 结论 该提取与甲酯化条件可用于气相色谱法鉴定羚羊角中脂类成分的种类及含量.
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| 关 键 词： | 羚羊角 脂类 甲酯化 色谱法,气相 |
| 收稿时间： | 2010-07-28 |
| 修稿时间： | 2010-09-20 |
Optimization of Extraction and Methylesterification of Lipids in Saigae Ataricae Cornu |
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| XU Ai-ren,HU Xiao-wei,MA Wei-cheng,YING Jin-yan. Optimization of Extraction and Methylesterification of Lipids in Saigae Ataricae Cornu[J]. Herald of Medicine, 2011, 30(4): 433-436. DOI: 10.3870/yydb.2011.04.007 |
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| Authors: | XU Ai-ren HU Xiao-wei MA Wei-cheng YING Jin-yan |
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| Affiliation: | XU Ai-ren1,HU Xiao-wei2,MA Wei-cheng1,YING Jin-yan1(1.Department of Pharmacy,Kidney Hospital of Ningbo City,Zhejiang Province,315100,China,2.Hangzhou Institute for Drug Control,Hangzhou,310017,China) |
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| Abstract: | Objective To establish the best way for extraction and methylesterification of lipids in Saigae Ataricae cornu. Methods The optimization of extraction and methylesterification for lipids in Saigae Ataricae cornu were investigated.The effects of extraction efficiency,catalyst dosage,temperature and time were studied on the basis of suitable extraction and methylesterification being selected. Results The best extraction method was modified chloroform-methanol one.The best methylesterification was by a sulfuri... |
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| Keywords: | Saigae Ataricae cornu Lipids Methylesterification Chromatography gas |
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