| 老智灵口服液治疗血管性痴呆的疗效观察 |
| |
| 引用本文： | 高唱,王景周,吴伟康,王琳,周红杰,高东,姚国恩,张莉莉. 老智灵口服液治疗血管性痴呆的疗效观察[J]. 中国组织工程研究与临床康复, 2002, 6(7): 1062-1063 |
| |
| 作者姓名： | 高唱 王景周 吴伟康 王琳 周红杰 高东 姚国恩 张莉莉 |
| |
| 作者单位： | 1.Daping Hospital of The Third Military Medicial University，Chongqing 400042，China; 2.Institute of Combination of TCM and Western Medicine，Sun Ya |
| |
| 基金项目： | 重庆市科委资助课题(1999～2001) |
| |
| 摘 要： | Vasculardementiaisakindofacquiredsyndromeduetocerebraldysfucntionfollowingvariouscerebrovasculardiseases．LoazhilingoralfluidwasdevelopedaccordingtoPafenglife－longingtangjiajianrecordedintheMedicalSecretesofanOfficial．Itpathologicaleffectisdefinewithoutobviousadverseandtoxicologicaleffects．Inthecurrentstudy，clinicaleffectandsafetyoflaozhilingoralfluidwereobserved．１Subjectandmethod１．１Subject４６VDpatientswithcompleteclinicalrecordwererecruitedfromJanuary１９９９toJuly２０００．All…
|
Observation on effect of Laozhiling oral liquid in treating vascular dementia |
| |
| GAO Chang ,WANG Jing zhou,WU Wei kang,WANG Lin,ZHOU Hong jie,GAO Dong,YAO Guo en,ZHANG Li li. Observation on effect of Laozhiling oral liquid in treating vascular dementia[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2002, 6(7): 1062-1063 |
| |
| Authors: | GAO Chang WANG Jing zhou WU Wei kang WANG Lin ZHOU Hong jie GAO Dong YAO Guo en ZHANG Li li |
| |
| Affiliation: | 1. Daping Hospital of The Third Military Medicial University,Chongqing 400042,China
2. Institute of Combination of TCM and Western Medicine,Sun Yat-sen University of Medical Sciences,Guangzhou 510089,China |
| |
| Abstract: | Objective To study the effect of Laozhiling (LZL)oral liquid in treating vascular dementia.Methods Patients were randomly divided into two groups,the 27 patients in the LZL treated group and the 19 patients in the control group treated by Jinnaduo injection with therapeutic course of 3 months.Changes of minimental state examination(MMSE),Hasegawa's Dementia Scale(HDS) ,activity of daily living(ADL) score and cerebrospinal fluid level of somatostatin(SS) ,β -endorphin(β -EP） and thrombospondin(TSP),glycoprotein IV(GPIV) were observed.Results The total effective rate in the LZL and Jinnaduo group were 66.66％ and 63.15％ ,the difference between the two groups was insignificant（ P >0.05） . MMSE,HDS score of patients and the content of SS,β -EP could be obviously elevated(P< 0.01)， the scores of ADL and TSP,GPIV could be markedly decreased(P< 0.01).Conclusion LZL has definite effect in treating VD,the therapeutic mechanism may be related with the actions of decreasing the platelet activation and improving the function of neuropeptides. |
| |
| Keywords: | laozhiling oral liquid vascular dementia platelet function cognition function |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
