重度卵巢过度刺激综合征1 3例临床分析

目的：总结重度卵巢过度刺激综合征（ovarian hy-perstimulation syndrome,OHSS）临床表现、发病机制及相应的治疗方法。方法：回顾性分析13例重度OHSS的临床资料。结果：重度OHSS发生在超排卵治疗后，临床表现为腹胀、恶心、腹水、胸水、少尿、血液浓缩、水电解质及酸碱平衡紊乱、氮质血症。经严密观察、输白蛋白、扩容及放胸腹水等治疗后治愈。移植日已出现OHSS者将胚胎冷冻保存。结论：防治重度OHSS的关键在于预防，一旦发生OHSS，经严密观察和及时治疗可治愈；迟发OHSS与妊娠有关。

Clinical analysis on the characteristics of 13 cases of severe ovarian hyperstimulation syndrome

Aim: To investigate the clinical characteristics, pathogenesis, and treatment of severe ovarian hyperstimulation syndrome (OHSS) .Methods: Clinical data of 13 OHSS patients were analyzed retrospectively. Results: Severe OHSS occurred after control led ovulation hyperstimulation treatment. the major manifestations for OHSS, were Abdominal distension, nausea, aseites, pleural effusion, oliguria, concentrated blood, hypoalbuminemia, electrolyte, acid-base disturbance, and azotemia, which could be controlled by intensive care, supplementation of albumin or plasma, volume expan-sion, and paracentesis. Cryopreserving all embryos on the day of embryos transfer if OHSS has occurred. Conclusion: Preventive measure of OHSS is very important and OHSS can be cured by intensive care and treatment. Late ovarian hyperstimulation syndrome is related to pregancy.