实热证、虚热证模型大鼠肝细胞琥珀酸脱氢酶活性研究

观察实热证、虚热证大鼠模型组与治疗组肝细胞线粒体琥珀酸脱氢酶(SDH)活性的变化。用紫外分光光度计测定肝细胞线粒体琥珀酸脱氢酶活性。结果表明：热证时(实热、虚热)SDH活性升高，经清热解毒、滋阴清热中药治疗后，SDH活性有所降低。说明：实热证、虚热证与机体能量代谢呈正相关，中药治疗有利于肝细胞线粒体呼吸亢进的恢复。

Study on the Activity of Succinate Dehydrogenase in Hepatic Cells of Rat Models of Excess Heat Syndrome and Deficiency Heat Syndrome

Rats were divided into control group, excess heat syndrome (EHS) group, and deficiency heat syndrome (DHS) group, and ultra violet spectrophotometer was used to determine the activity of succinate dehydrogenase (SDH) in the hepatic cell mitochondria in the rats of these groups. The results showed that SDH increased in both EHS group and DHS group, but it decreased in the two groups after traditional Chinese drugs (for clearing away heat and dispelling toxic substances, and for nourishing yin and clearing away heat) were given. The results imply that there is a positive correlation between these two syndromes (EHS and DHS) and the energy metabolism in the body; and the treatment with traditional Chinese drugs benefits the restoration of mitochondrial hyperactive respiration of hepatic cells to the normal level.