| 氟伏沙明合并氯氮平治疗强迫症的疗效比较 |
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| 引用本文： | 金珠玛.氟伏沙明合并氯氮平治疗强迫症的疗效比较[J].四川精神卫生,2007,20(1):15-16. |
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| 作者姓名： | 金珠玛 |
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| 作者单位： | 210029,南京医科大学附属脑科医院精神科三病区 |
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| 摘 要： | 目的探讨氟伏沙明合并氯氮平治疗强迫症的疗效。方法45例强迫症患者随机分为氟伏沙明合并氯氮平治疗组和单独氟伏沙明治疗组。疗程8周。采用强迫症量表（Y—BOCS）、汉密尔顿焦虑量表（HAMA）、汉密尔顿抑郁量表（HAMD）评定疗效。结果治疗结束时两组Y—BOCS、HAMA、HAMD的评分均显著降低，更以合并氯氮平组明显。结论氟伏沙明合并氯氮平治疗强迫症可以增加疗效。
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| 关 键 词： | 氯氮平 氟伏沙明 强迫症 |
| 文章编号： | 1007-3256（2007）01-0015-02 |
| 收稿时间： | 2006-09-07 |
| 修稿时间： | 2006-09-07 |
Comparative analysis of fluvoxamine combining with clozapine in the treatment of obsessive-compulsive disorder |
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| JIN Zhuma.Comparative analysis of fluvoxamine combining with clozapine in the treatment of obsessive-compulsive disorder[J].Sichuan Mental Health,2007,20(1):15-16. |
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| Authors: | JIN Zhuma |
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| Institution: | Department of Psychiatry,Affiliated Brain Hospital of Nanfing Medical University,Nanjing 210029, China |
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| Abstract: | Objective To investigate the efficacy of fluvoxamine combining with clozapine in the treatment of obsessive-compulsive disorder(OCD).Method 45 patients with OCD were randomly treated with fluvoxamine combining with clozapine(n=25) and fluvoxamine only(n=20).The efficacy was measured with Yale-Brown obsessive compulsive scale(Y-BOCS),Hamilton anxiety scale(HAMA)and Hamilton depression scale(HAMD).Results There were significant differences between two groups in overall response showed by the reduction rate of Y-BOCS,HAMA and HAMD total scores.Conclusion It is suggested that fluvoxamine combining with clozapine have a superior effectiveness in the treatment of OCD. |
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| Keywords: | Clozapine Fluvoxamine Obsessive-compulsive disorder |
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