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蒙药列当的化学成分研究
引用本文:邵红霞,杨九艳,鞠爱华.蒙药列当的化学成分研究[J].中华中医药杂志,2011(1):129-131.
作者姓名:邵红霞  杨九艳  鞠爱华
作者单位:内蒙古大学生命科学学院;内蒙古精神卫生中心药械科;内蒙古医学院药学院;
基金项目:内蒙古大学高层次引进人才科研启动基金资助项目(No.Z20070104)~~
摘    要:目的:研究蒙药列当(Orobanche coerulescens Steph)的化学成分,为进一步明确其中的有效成分奠定基础。方法:利用普通硅胶柱色谱、大孔树脂柱色谱、Sephadex LH-20色谱技术及重结晶等方法进行分离、纯化,并利用波谱技术和理化性质确定了化合物的结构。结果:从中分离得到9个化合物,分别鉴定为:甘露醇①,β-谷甾醇②,豆甾醇③,二十烷酸-1-甘油酯④,β-胡萝卜苷⑤,琥珀酸⑥,Crenatoside⑦,麦角甾苷⑧,D-松醇⑨。结论:其中化合物③,④,⑦,⑧,⑨为首次从该植物中获得。

关 键 词:列当  列当科  化学成分  Crenatoside  麦角甾苷

Studies on chemical constituents of Mongolian medicine Orobanche coerulescens
SHAO Hong-xia,YANG Jiu-yan,JU Ai-hua.Studies on chemical constituents of Mongolian medicine Orobanche coerulescens[J].China Journal of Traditional Chinese Medicine and Pharmacy,2011(1):129-131.
Authors:SHAO Hong-xia  YANG Jiu-yan  JU Ai-hua
Institution:SHAO Hong-xia1,2,YANG Jiu-yan1,JU Ai-hua3(1College of Life Science,Inner Mongolia University,Huhhot 010021,China,2Department of Pharmacy,Inner Mongolia Mental Health Center,Huhhot 010010,3College of Pharmacy,Inner Mongolia Medical College,Hohhot 010059,China)
Abstract:Objective: To study the chemical constituents of mongolian medicine Orobanche coerulescens Steph in order to clarify the effective constituents.Methods: The chemical constituents were purified by silica gel,porous resin,Sephadex LH-20 and recrysta Uization and then the structures were determined by spectralanalyses.Results: Nine compounds were obtained and determined as D-mannitol①β-sitosterol②,tigmasterol③,Glyceryl arachidate④,β-Daucosterol⑤,succinicacid⑥,Crenatosid⑦,Acteoside⑧,D-pinitol⑨.Conclusion: Compounds ③,④,⑦,⑧,⑨ were obtained from this plant for the first time.
Keywords:Orobanche coerulescens  Orobanchaceae  Chemical constituents  Crenatoside  Acteoside  
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