| 维药恰玛古蜜膏和恰玛古粉药效学对比研究 |
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| 引用本文： | 安熙强,马媛,张涛,贾鸿雁,孙艳,斯建勇. 维药恰玛古蜜膏和恰玛古粉药效学对比研究[J]. 中华中医药杂志, 2011, 0(1): 141-143 |
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| 作者姓名： | 安熙强 马媛 张涛 贾鸿雁 孙艳 斯建勇 |
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| 作者单位： | 新疆维吾尔自治区药物研究所食品检测研究室;新疆柯坪圣泉实业有限公司;石河子大学药学院;中国医学科学院北京协和医学院药用植物研究所; |
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| 基金项目： | 乌鲁木齐市人才工程计划项目(No.P101310002)~~ |
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| 摘 要： | 目的:研究恰玛古蜜膏和恰玛古粉对小鼠免疫功能的影响。方法:测定小鼠耳廓肿胀度,观察对二硝基氯苯诱导小鼠迟发型超敏反应的影响;通过紫外分光光度法测定观察小鼠单核巨噬细胞对血流中碳粒的清除能力;紫外分光光度法测定小鼠血清中IgM抗体水平;镜检计数观察小鼠腹腔巨噬细胞吞噬鸡红细胞的能力。结果:恰玛古蜜膏14g/kg剂量与恰玛古粉12g/kg剂量能明显抑制二硝基氯苯诱导的小鼠迟发型超敏反应、促进小鼠血清中IgM抗体的生成,恰玛古粉6g/kg和12g/kg剂量能明显提高小鼠单核巨噬细胞对血流中碳粒的清除能力、提高小鼠腹腔巨噬细胞吞噬鸡红细胞的能力。结论:恰玛古蜜膏和恰玛古粉均可调节机体的免疫功能,恰玛古粉的作用略优于恰玛古蜜膏。
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| 关 键 词： | 恰玛古 小鼠 免疫调节 |
Comparative study of pharmacodynamics on uighur folk medicine Brassica campestris L.ointment and Brassica campestris L.powder |
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| AN Xi-qiang,MA Yuan,ZHANG Tao,JIA Hong-yan,SUN Yan,SI Jian-yong. Comparative study of pharmacodynamics on uighur folk medicine Brassica campestris L.ointment and Brassica campestris L.powder[J]. China Journal of Traditional Chinese Medicine and Pharmacy, 2011, 0(1): 141-143 |
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| Authors: | AN Xi-qiang MA Yuan ZHANG Tao JIA Hong-yan SUN Yan SI Jian-yong |
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| Affiliation: | AN Xi-qiang1,MA Yuan1,ZHANG Tao1,JIA Hong-yan2,SUN Yan3,SI Jian-yong4(1Food Inspection Laboratory,Xinjiang Institute of Meteria Medica,Urumchi 830004,China,2The Company Of Health Products of Ke Ping Sheng Quan,Akesu 830000,3School of Pharmacy,Shihezi University,Shihezi 832000,4Department of Phytochemistry,Chinese Academy of Medical Sciences and Peking Union Medical College,Institute of Medicinal Plant Development,Beijing 100193,China) |
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| Abstract: | Objective: To study the role of Brassica campestris L.ointment and B.campestris L.powder on immune function in mice.Method: Through the delayed type hypersensitivity(DTH) induced by DNCB determine umefaction of ear;The influence on carbongranular clearance ability of mononuclear macrophage in mice was determined by ultraviolet spectrophotometry;the IgM level was determined by ultraviolet spectrophotometry;the ability of englobing red blood cell of chicken of peritoneal macrophage in mice abserve by microsco... |
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| Keywords: | Brassica campestris L. Mice Immune function |
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