| 氢化可的松发酵液3次提取产物含量的研究 |
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| 引用本文： | 孙丽丽,董艳苓,袁东超,杨云沛. 氢化可的松发酵液3次提取产物含量的研究[J]. 药物生物技术, 2007, 14(2): 139-140 |
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| 作者姓名： | 孙丽丽 董艳苓 袁东超 杨云沛 |
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| 作者单位： | 1. 天津市津津药业有限公司,天津,300380
2. 天津市津津药业有限公司,天津,300380;天津市药品检验所,天津,300070 |
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| 摘 要： | 通过用HPLC对氢化可的松发酵液不同提取次数所得产物进行分析，对不同杂质含量的提取物用不同的方法进行分离纯化，所得氢化可的松成品的含量提高1．0％，收率提高6．0％，生产周期缩短20％。
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| 关 键 词： | 氢化可的松 发酵液 提取次数 含量 |
| 文章编号： | 1005-8915（2007）02-0139-02 |
| 修稿时间： | 2006-05-292006-07-03 |
Study on Assay of Hydrocortisone Product from Ferment Liquid |
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| SUN Li-li,DONG Yan-ling,YUAN Dong-Chao,YANG Yun-pei. Study on Assay of Hydrocortisone Product from Ferment Liquid[J]. Pharmaceutical Biotechnology, 2007, 14(2): 139-140 |
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| Authors: | SUN Li-li DONG Yan-ling YUAN Dong-Chao YANG Yun-pei |
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| Affiliation: | 1. Tianjin Jinjin Pharmaceutical Co Ltd, Tianjin 300380, China; 2. Tianjin Institute for Drug Control, Tianjin 300070, China |
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| Abstract: | The product which comes from hydrocortisone ferment liquid, was analyzed by HPLC. Product was separated by different purification methods, content of hydrocortisone was increased by 1.0%, yield increased by 6.0%, and the period of production was reduced 20%. |
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| Keywords: | Hydrocortisone Ferment liquid Separate times Assay |
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