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克林霉素磷酸酯致耳鸣和三叉神经痛
引用本文:李勉珊,梁淑文,刘刚,冯瑞娟.克林霉素磷酸酯致耳鸣和三叉神经痛[J].药物不良反应杂志,2008,10(2):115-115.
作者姓名:李勉珊  梁淑文  刘刚  冯瑞娟
作者单位:[1]解放军306医院药学部,北京 100101; [2]解放军306医院干部病房,北京 100101; [3]解放军306医院干部病房3病区,北京 100101
摘    要:1例40岁肺部感染男性患者,给予克林霉素磷酸酯600mg静脉滴注治疗后出现轻度耳鸣。6h后第2次滴注,又出现耳呜,伴恶心呕吐,之后耳鸣加重和左侧面部电击样痛。疼痛发作共10余次,每次持续数秒至2min,诊为三叉神经痛。停用克林霉素,12h后症状缓解。

关 键 词:克林霉素磷酸酯  耳鸣  三叉神经痛

Tinnitus and trigeminal neuralgia caused by clindamycin phosphate
Li Mianshan,Liang Shuwen,Liu Gang,Feng Ruijuan.Tinnitus and trigeminal neuralgia caused by clindamycin phosphate[J].Adverse Drug Reactions Journal,2008,10(2):115-115.
Authors:Li Mianshan  Liang Shuwen  Liu Gang  Feng Ruijuan
Institution:Li Mianshan, Liang Shuwen, Liu Gang, Feng Ruijuan(l.Department of Pharmacy, 2.Cadre Ward Section 4,3.Cadre Ward Section 3, 306th Hospital of PLA, Beijing 100101, China)
Abstract:A 40-year-old man with pulmonary infection developed mild tinnitus after intravenous infusion of clindamycin phosphate 600 rag. Six hours later, he received the second infusion of clindamycin, his tinnitus reappeared accompanied with nausea and vomiting, and then aggravated tinnitus and lightning pain in the left face occurred. The pain repeated up to 10 times or more and lasted for several seconds to two minutes, and trigeminal neuralgia was diagnosed. Clindamycin was discontinued. Twelve hours later, his symptoms were relieved.
Keywords:clindamycin phosphate  tinnitus  trigeminal neuralgia
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