Hyperthyroidism secondary to a pituitary adenoma secreting TSH, FSH, alpha-subunit and GH |
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| Authors: | A. W. Patrick S. L. Atkin J. MacKenzie P. M. Foy M. C. White I. A. MacFarlane |
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| Affiliation: | Departments of Endocrinology, Walton Hospital, Liverpool;Departments of Neurological Sciences, Walton Hospital, Liverpool;Department of Medicine, Royal Liverpool University Hospital, Liverpool, UK |
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| Abstract: | A 51-year-old man had been treated for hyperthyroidism with antithyroid drugs for 8 years. He was then found to have a large pituitary adenoma with biochemical evidence of overproduction of TSH, FSH and alpha-subunit. Subsequent immunocytochemical and tissue culture studies confirmed secretion of these hormones. In addition, the tumour stained for GH and was capable of GH production in vitro. This combination of hormones produced by a pituitary adenoma has not been previously reported. |
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