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Arginine butyrate increases the cytotoxicity of DAB(389)IL-2 in leukemia and lymphoma cells by upregulation of IL-2Rbeta gene |
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| Authors: | Shao Richard H Tian Xuejun Gorgun Gullu Urbano Alexander G Foss Francine M |
| Affiliation: | Hematology–Oncology Department, New England Medical Center, Tufts University, Boston, MA, USA |
| Abstract: | |
| Keywords: | T-cell lymphoma/leukemia Cutaneous T-cell lymphoma (CTCL) DAB389IL-2 ONTAK Interleukin-2 (IL-2) IL-2 receptor (IL-2R) Arginine butyrate Histone deacetylase (HDAC) inhibitor Signal transduction pathway |
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