| 缺血性脑卒中患者血浆NO浓度变化的研究 |
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| 引用本文： | 王立,徐俊,陈月琴.缺血性脑卒中患者血浆NO浓度变化的研究[J].临床神经病学杂志,2001,14(5):269-271. |
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| 作者姓名： | 王立 徐俊 陈月琴 |
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| 作者单位： | 南京医科大学附属脑科医院徐俊现为中山医科大学博士生 |
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| 摘 要： | 目的 研究不同类型的缺血性脑卒中患者的血浆一氧化氮（NO）浓度变化及其临床意义。方法 采用硝酸还原酶法测定230例脑梗死患者、103例腔隙性脑梗死患者以及169名正常对照者的血浆NO浓度。结果 脑梗死组血浆NO浓度与另两组相比显著增高（均P＜0．01），而腔隙性脑梗死患者的血浆NO浓度低于对照组（P＜0．05）。结论 脑梗患者急性期血浆NO浓度可作为缺血损害的一个参考指标；而腔隙性脑梗死组NO浓度下降反映患者的高血压等基础病变的存在。
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| 关 键 词： | 缺血性脑卒中 NO 血浆 浓度 |
| 文章编号： | 1004-1648(2001)05-0269-03 |
| 修稿时间： | 2000年9月27日 |
Study on the changes of NO plasma level in patients with ischemic stroke |
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| Wang Li,Xu Jun,Chen Yueqin.Study on the changes of NO plasma level in patients with ischemic stroke[J].Journal of Clinical Neurology,2001,14(5):269-271. |
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| Authors: | Wang Li Xu Jun Chen Yueqin |
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| Institution: | Wang Li,Xu Jun,Chen Yueqin.Brain Hospital Affiliated to Nanjing Medical University,Nanjing 210029 |
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| Abstract: | Objective To study the changes of NO plasma levels in patient with ischemic stroke(IS) of different types.Methods Using HNO 3 deoxidize enzyme method, we examined the levels of plasma NO in 230 patients with cerebral infarction, 103 patients with lacular cerebral infarction and 169 normal controls.Results In cerebral infarction group, the level of plasma NO was significant higher than the two other groups ( P <0 001), but the patients with the lacunar cerebral infarction had lower NO level than the controls( P <0 05). Conclusion The level of plasma NO in the patients with cerebral infarction of acute stage might be a reference index for ischemic damage, and the lower level of NO showed the existence of hypertension in lacunar cerebral infarction group. |
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| Keywords: | Ischemic stroke Nitric oxide Plasma |
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