| 乙型肝炎病毒致肝细胞癌发生机制研究进展 |
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| 引用本文： | 郭恩爽,周福元.乙型肝炎病毒致肝细胞癌发生机制研究进展[J].实用肝脏病杂志,2014(4):437-440. |
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| 作者姓名： | 郭恩爽 周福元 |
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| 作者单位： | 广州市南方医科大学南方医院感染内科,510515 |
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| 摘 要： | 肝细胞癌（HCC）的发生与乙型肝炎病毒（HBV）感染密切相关。HBV感染所致的炎症反应、HBV X基因及其产物X蛋白、核心启动子突变、前S2区突变、剪接特异性蛋白等均可能参与HCC的发生发展。
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| 关 键 词： | 肝细胞癌 乙型肝炎病毒 发生机制 |
Hepatitis B virus- associated mechanisms of hepatocellular carcinoma |
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| GuoEnshuang,Zhou Fuyuan.Hepatitis B virus- associated mechanisms of hepatocellular carcinoma[J].Journal of Clinical Hepatology,2014(4):437-440. |
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| Authors: | GuoEnshuang Zhou Fuyuan |
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| Institution: | ( Department of Infectious Diseases,Nanfang Hospital,Affiliated to Southern Medical University,Guangzhou 510515 China) |
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| Abstract: | The infection of hepatitis B virus （HBV） plays an important role in the occurrence of hepatocellular carcinoma （HCC）. Multiple factors may be involved in the hepatocarcinogenesis of HBV-related HCC,such as inflammatory response,HBV X gene and its protein,the mutation of HBV core promoter and pre-S 2 genes,HBV spliced protein and so on. We will discuss some progresses in this field. |
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| Keywords: | Hepatocellular carcinoma Hepatitis B virus Mechanisms |
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