Androgen production by testes of Gallus domesticus during postembryonic development |
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Authors: | Florencia E Galli O Irusta GF Wassermann |
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Institution: | Laboratorio de Esteroides, Instituto de Biología y Medicina Experimental, Obligado 2490, Buenos Aires, Argentina |
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Abstract: | Cock testes incubated with labeled pregnenolone or progesterone as substrates produced testosterone as the main compound. The formation of 17α-hydroxyprogesterone was greater with progesterone as precursor, but the production of radioactive 20β-dihydroprogesterone and androstenedione was similar with either substrate. Testes from 1-, 21-, and 40-day-old chicks incubated with progesterone as a substrate had a very low testosterone: androstenedione production ratio (0.05). In mature animals, however, more testosterone than androstenedione was produced from radioactive progesterone and the production ratio testosterone: androstenedione was 24. |
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