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Reliability and validity of Thai versions of the MOS-HIV and SF-12 quality of life questionnaires in people living with HIV/AIDS
Authors:Suwat Chariyalertsak  Tanyaporn Wansom  Surinda Kawichai  Cholthicha Ruangyuttikarna  Verne F Kemerer  Albert W Wu
Affiliation:(1) Research Institute for Health Sciences, Chiang Mai University, CMU, PO Box 80, Chiang Mai, 50202, Thailand;(2) Department of Medicine, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, B1 N 1st Floor, Baltimore, MD 21224, USA;(3) UN Trust Fund to End Violence Against Women, 2345 Crystal Drive, Suite 301, Arlington, VA 22202, USA;(4) Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway, Rm. 653, Baltimore, MD 21205, USA
Abstract:

Background/Aim  

As Thai people living with HIV/AIDS gain increasing access to antiretroviral (ARV) therapy, it is important to evaluate the impact this has not only on clinical outcomes, but also on patients' functional status and well-being. In this study, we translated, culturally adapted and tested the reliability and validity of two widely-used health-related quality of life questionnaires - the MOS-HIV Health Survey and the SF-12 - in people living with HIV/AIDS in Northern Thailand. Methods: Questionnaires were administered to 100 patients at community hospital outpatient ARV clinics in northern Thailand. Reliability was estimated using Cronbach's alpha, while evidence for validity was tested using known-groups comparison based on CD4 group, symptom distress score, bed days and days of reduced activity in the past three months.
Keywords:
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