表观弥散系数对脑淋巴瘤与胶质母细胞瘤的鉴别诊断

目的 探讨脑淋巴瘤与胶质母细胞瘤(GMB)的弥散加权成像(DWI)影像学特征以及表观弥散系数(ADC值)对其的鉴别诊断价值.方法 回顾性分析经病理证实的12例脑原发性淋巴瘤和15例GMB的常规MRI及DWI影像学表现,测量肿瘤实质的ADC值及rADC值,并进行组间对照分析.结果 12例淋巴瘤肿瘤实质在DWI上呈稍高或高...

Differential diagnosis between cerebral lymphoma and gliomas multiblastoma by using of apparent diffusion coefficient

Objective：To investigate diffusion-weighted MR images（DWI） features of primary intracerebral lymphoma and gliomas multiblastoma（GMB）,and to further assess the differentiation between them by using apparent diffusion coefficient（ADC） value.Materials and Methods：Twelve patients with pathologically proved primary intra-cerebral lymphoma and 15 with GMB underwent MR examination,including DWI.The ADC values and ratio of ADC values（rADC） in solid parenchyma in all tumors were measured and compared between groups by two neuroradiologists.Results：Lymphoma showed slight-high or high intensity signal in DWI,and GMB were iso-or low intensity signal.Compared to normal appearing white matter,ADC values of lymphoma were significantly decreased （0.593±0.176）×10-3 mm2/s,（0.773±0.057）×10-3 mm2/s,P=0.006],whereas those of GMB became obviously increased （0.975±0.118）×10-3 mm2/s,（0.768±0.077）×10-3 mm2/s,P〈0.001].ADC values and rADC values were significantly different between lymphoma and GMB.Cutoff values to differentiate them were 0.805×10-3 mm2/s for ADC and 1.08 for rADC respectively.Conclusion：As a complementary method to conventional MR sequences,measurement of ADC value in DWI is helpful in the differentiated diagnosis on cerebral lymphoma and GMB.