胎儿胼胝体发育不全的MRI诊断

目的 探讨MRI在胎儿胼胝体发育不全(ACC)诊断中的应用价值.方法 39例孕妇,年龄19～35岁;孕龄22～39周,平均29周.产前常规行超声(US)检查后24～48 h内行MR检查,采用二维快速平衡稳态采集(2D FIESTA)序列、单次激发快速自旋回波(SSFSE)序列、快速反转恢复运动抑制(FIRM)序列及扩散...

MRI diagnosis of fetal corpus callosum agenesis

Objective： To explore the diagnostic value of MRI on fetal agenesis of corpus callosum （ACC）. Materials and Methods： Thirty-nine pregnant women, aged from 19 to 35 years （average 29 years） and with gestation from 22-39 weeks （average 29 weeks） were studied with a 1.5 T superconductive MR unit within 24 to 48 hours after ultrasound examination. The imaging protocol included fast-imaging employing steady-state acquisition （FIF, STA）, single-shot fast spin echo （SSFSE）, Tl - weighted fast inversion recovery motion insensitive （FIRM） and diffusion-weighted imaging （DWI） sequences in the axial, frontal, and sagittal planes relative to the fetal brain, thorax, abdomen, especially brain. Prenatal US and MR imaging findings were compared with postnatal brain MRI diagnosis （20 fetuses） or postmortem examination （19 fetuses）. Results： In 39 cases of ACC, 32 cases were complete agenesis and 7 were partial agenesis; 31 cases were simple ACC, 8 cases were with other malformations. Follow-up results were consistent with prenatal MRI diagnosis, prenatal US missed or misdiagnosed 19 cases of ACC or combined deformity. Conclusion Fetal MRI is currently the best means of diagnosing ACC. It can directly show the existence of the corpus callosum, and better show the combined brain malformation of ACC.