| 磁共振成像及对比剂在细胞移植中的研究进展 |
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| 引用本文： | 徐波,梁碧玲,邓宇斌. 磁共振成像及对比剂在细胞移植中的研究进展[J]. 磁共振成像, 2011, 2(3): 210-214. DOI: 10.3969/j.issn.1674-8034.2011.03.010 |
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| 作者姓名： | 徐波 梁碧玲 邓宇斌 |
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| 作者单位： | 1. 中山大学中山医学院病理学与病理生理学教研室,广州,510080
2. 中山大学孙逸仙纪念医院放射科,广州,510120 |
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| 基金项目： | 国家自然科学基金项目，教育部博士点基金 |
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| 摘 要： | 随着细胞移植研究的不断深入,细胞移植在临床治疗中的应用逐渐增多.但不论是在科研工作还是临床治疗中进行细胞移植,都需要监测移植后细胞的命运.磁共振成像技术具有无创伤性、时间连续性等优点,是在活体上对移植细胞进行连续多时间点监测的理想方法之一.应用磁共振对比剂在体外标记细胞后将细胞移植入动物体内,可通过磁共振成像追踪移植细...
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| 关 键 词： | 磁共振成像 对比剂 细胞标记 细胞移植 |
Applications of cellular MRI and cell labeling contrast agents in cell transplantation |
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| XU Bo,LIANG Bi-ling,DENG Yu-bin. Applications of cellular MRI and cell labeling contrast agents in cell transplantation[J]. Chinese Journal of Magnetic Resonance Imaging, 2011, 2(3): 210-214. DOI: 10.3969/j.issn.1674-8034.2011.03.010 |
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| Authors: | XU Bo LIANG Bi-ling DENG Yu-bin |
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| Affiliation: | 1Institute of Pathophysiology,SUN Yat-sen University,Guangzhou 510080,China 2Department of Radiology;Sun Yat-sen Memorial Hospital,Guangzhou 510120,China |
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| Abstract: | The clinical applications of cell transplantation increase gradually along with the developments of preclinical researches.However,it is necessary to track the fate of transplanted cells in both clinical applications and preclinical researches.Magnetic resonance imaging is non-invasive and time continuous,and is an ideal method to continuous track transplanted cells in vivo.By labeling the cells with MRI contrast agents,we can monitor the migration,distribution and functional status of transplanted cells with MRI.Here we reviewed the progresses of magnetic resonance imaging and cell-labeling contrast agents in cell transplantation. |
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| Keywords: | Magnetic resonance imaging； Contrast agent； Cell labeling； Cell transplantation； |
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