Characterization of a novel HLA-DQB1 allele, DQB1*020102 |
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| Authors: | Lv F Gao J Lin J Liu Z Xu Y Ren X Zhang H Xu A |
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| Institution: | Key Laboratory of Genetic Engineer of MOE, Department of Biochemistry, College of Life Sciences, Sun Yat-sen (Zhongshan) University, Guangzhou, China. |
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| Abstract: | A novel human leukocyte antigen (HLA)-DQB1 allele, DQB1*020102, was detected in a 28-year-old woman of Han ethnic in Guangzhou, China. Compared with HLA-DQB1*020101 and HLA-DQB1*0202, they differed in only one nucleotide at the position 167 (C to T) of exon 2, which was a highly conserved position. This is a synonymous mutation, which does not cause any change in the amino acid sequence of mature protein. |
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| Keywords: | DQB1*020102 HLA-DQB1 |
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