Male sexual function and lower urinary tract symptoms after laparoscopic total mesorectal excision |
| |
Authors: | S O Breukink M F van Driel J P E N Pierie C Dobbins T Wiggers W J H J Meijerink |
| |
Institution: | (1) Department of Surgery, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands;(2) Department of Urology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands;(3) Department of Surgery, Medical Centre Leeuwarden, Leeuwarden, The Netherlands;(4) Department of Surgery, The Queen Elizabeth Hospital, Adelaide, Australia;(5) Department of Surgery, VU Medical Centre, Amsterdam, The Netherlands;(6) 42 Marlboroughstreet, Brighton, South Australia, 5048, Australia |
| |
Abstract: | Background and aims The aim of this study was to investigate sexual function and the presence of lower urinary tract symptoms (LUTS) in male patients
with rectal cancer following short-term radiotherapy and laparoscopic total mesorectal excision (LTME) by physical and psychological
measurements.
Materials and methods Sexual function and LUTS were assessed by the use of questionnaires International Index of Erectile Function (IIEF), International
Prostate Symptom Score]. Sexual function was further assessed by the use of pharmaco duplex ultrasonography of the cavernous
arterial blood flow and nocturnal penile tumescence and rigidity monitoring (NPTR). All investigations were performed prior
to the start of preoperative radiotherapy and 15 months after surgery.
Results Nine patients (mean age 60 years) participated. Erectile function was maintained in 71% and ejaculation function in 89%. Compared
with pre-operative scores on the IIEF, a significant deterioration in intercourse satisfaction was seen following radiotherapy
and LTME (7.9 vs 10.3, p = 0.042), but overall satisfaction remained unchanged (8.0 vs 7.0, p = 0.246). NPTR parameters (duration of erectile episodes, duration of tip rigidity ≥60%) decreased following radiotherapy
and LTME. Patients reported a deterioration in micturition frequency (2.0 vs 1.0, p = 0.034) and quality of life due to urinary symptoms (8.0 vs 1.8, p = 0.018).
Conclusion Based on these first preliminary findings, data suggest that 15 months after short-term radiotherapy and LTME in men with
rectal cancer, objectively assessed sexual dysfunction was considerable, but overall sexual satisfaction had not changed. |
| |
Keywords: | Sexual function Lower urinary tract symptoms Laparoscopy Colorectal cancer Total mesorectal excision |
本文献已被 PubMed SpringerLink 等数据库收录! |
|