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Post-transplant lymphoproliferative disorder following cytomegalovirus reactivation in a lung recipient
Authors:Akihiro Aoyama  Mitsugu Omasa  Nobuyuki Kondo  Fengshi Chen  Hiroshi Date  Toru Bando
Institution:(1) Pulmonary Institute, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel;(2) Gastrointestinal Institute, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel;(3) Department of Cardiothoracic Surgery, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel;(4) Department of Internal Medicine, Shaare-Zedek Medical Center, Jerusalem, Israel;
Abstract:Post-transplant lymphoproliferative disorder (PTLD) is a life-threatening complication after lung transplantation, for which several risk factors including pretransplant seronegativity for Epstein-Barr virus are known. However, the impact of cytomegalovirus on PTLD remains to be determined. Here, we describe a case of Epstein-Barr virus-associated polymorphic PTLD that developed shortly after treatment for cytomegalovirus reactivation in a lung transplant recipient who was preoperatively seropositive for both cytomegalovirus and Epstein-Barr virus.
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