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IGT和糖尿病视网膜病变关系的研究进展
引用本文:柏丽娜,张学东.IGT和糖尿病视网膜病变关系的研究进展[J].眼科新进展,2006,26(12):945-947.
作者姓名:柏丽娜  张学东
作者单位:400016,重庆市,重庆医科大学附属第一医院眼科
摘    要:糖耐量低减(i mpaired glucose tolerance,IGT)是介于正常和糖尿病之间的中间状态,其所致的糖尿病视网膜病变越来越受到人们的关注。本文主要叙述了IGT患者糖尿病视网膜病变的发病率,从高血糖、胰岛素抵抗和高胰岛素血症、游离脂肪酸和脂肪细胞因子释放增多这几个方面阐述了IGT时糖尿病视网膜病变的发病机理,强调对IGT患者进行早期干预的重要性。

关 键 词:糖耐量低减  糖尿病视网膜病变  高血糖  游离脂肪酸  胰岛素抵抗
文章编号:1003-5141(2006)12-0945-03
收稿时间:2005-09-28
修稿时间:2005-12-29

Research progress on the relationship of impaired gluc
BAI Li-Na,ZHANG Xue-Dong.Research progress on the relationship of impaired gluc[J].Recent Advances in Ophthalmology,2006,26(12):945-947.
Authors:BAI Li-Na  ZHANG Xue-Dong
Institution:From the Department of Ophthalmology, the First Affiliated Hospital of Chongqing Medical and Science University, Chongqing 400016, China
Abstract:Impaired glucose tolerance(IGT)is the intermediate state between normal glucose and diabetes.People has drawn increasing attention to the diabetic retinopathy(DR)caused by IGT.This article summaries the prevalence of the DR caused by IGT and reviews the mechanism of DR caused by IGT from following aspects:hyperglycemia,insulin resistance and hyperinsulinemia,increasing release of free fat acid and adipocytokines,and emphasizes the importance of early intervention in IGT patients.
Keywords:impaired glucose tolerance  diabetic retinopathy  hyperglycemia  free fat acid  insulin resistance
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