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Sensitivity and Specificity of the Beck Depression Inventory-II in Persons With Traumatic Brain Injury
Authors:Beeta Y. Homaifar  Lisa A. Brenner  Peter M. Gutierrez  Jeri F. Harwood  Caitlin Thompson  Christopher M. Filley  James P. Kelly  Lawrence E. Adler
Affiliation:a Veterans Affairs VISN 19 Mental Illness Research, Education and Clinical Center, Denver, CO
b Department of Physical Medicine and Rehabilitation, University of Colorado Denver, School of Medicine, Denver, CO
c Department of Psychiatry, University of Colorado Denver, School of Medicine, Denver, CO
d Department of Pediatrics, University of Colorado Denver, School of Medicine, Denver, CO
e Department of Neurology, University of Colorado Denver, School of Medicine, Denver, CO
f Department of Neurosurgery, University of Colorado Denver, School of Medicine, Denver, CO
g Department of Psychiatry, University of Rochester Medical Center, Rochester, NY
h Veterans Affairs Eastern Colorado Health Care System, Denver, CO
i Department of Biostatistics and Informatics, School of Public Health, Denver, CO
Abstract:Homaifar BY, Brenner LA, Gutierrez PM, Harwood JF, Thompson C, Filley CM, Kelly JP, Adler LE. Sensitivity and specificity of the Beck Depression Inventory-II in persons with traumatic brain injury.

Objectives

Our objective was to examine the Beck Depression Inventory-II (BDI-II) in a traumatic brain injury (TBI) sample using a receiver operating characteristic (ROC) curve to determine how well the BDI-II identifies depression. An ROC curve allows for analysis of the sensitivity and specificity of a diagnostic test using various cutoff points to determine the number of true positives, true negatives, false positives, and false negatives.

Design

This was a secondary analysis of data gathered from an observational study. We examined BDI-II scores in a sample of 52 veterans with remote histories of TBI.

Setting

This study was completed at a Veterans Affairs (VA) Medical Center.

Participants

Participants were veterans eligible to receive VA health care services.

Interventions

Not applicable.

Main Outcome Measures

Outcome measures included the BDI-II and the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-IV).

Results

We generated an ROC curve to determine how well the BDI-II identifies depression using the SCID-IV as the criterion standard for diagnosing depression, defined here as a diagnosis of major depressive disorder. Results indicated a cutoff score of at least 19 if one has a mild TBI or at least 35 if one has a moderate or severe TBI. These scores maximize sensitivity (87%) and specificity (79%).

Conclusions

Clinicians working with persons with TBI can use the BDI-II to determine whether depressive symptoms warrant further assessment.
Keywords:Brain injuries   Depression   Rehabilitation   Veterans
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