艾纳香中的黄酮类化学成分

目的:研究艾纳香Blumea balsamifera中的黄酮类化学成分.方法:运用硅胶、Sephadex LH-20柱色谱对艾纳香中的化学成分进行分离,通过理化常数和波谱数据分析鉴定化合物.结果:从艾纳香中分离并鉴定了12个化合物,分别为3,3’,5,5’,7-五羟基二氢黄酮(1),3,3’,4’,5-四羟基-7-甲氧基二氢黄酮(2),金圣草素(3),3’,4’,5-三羟基-3,7-二甲氧基黄酮(4),香叶木素(5),3,3’,4’,5-四羟基-7-甲氧基黄酮(6),3,5-二羟基-3’,4’,7-三甲氧基黄酮(7),chrysosplenol C(8),3,3’,5-三羟基-4’,7-二甲氧基二氢黄酮(9),艾纳香素(10),3,3’,5,7-四羟基-4’-甲氧基二氢黄酮(11),3’,5,5’,7-四羟基二氢黄酮(12).结论:化合物1,3～5,8为首次从该属植物中分离得到;化合物6,7为首次从该植物中分离得到.

Study on Flavonoids Constituents of Blumea balsamifera

Objective:To study the flavonoids constituents of the aerial parts of Blumea balsamifera.Method:The compounds were isolated and purified by silica gel,Sephadex LH-20,medium pressure column chromatography,and their structures were elucidated by spectral methods and chemical analysis.Result:Twelve compounds were isolated and their structures were identified as 3,3’,5,5’,7-pentahydroxyflavanone(1),3,3’,4’,5-tetrahydroxy-7-methoxyflavanone(2),chrysoeriol(3),3’,4’,5-trihydroxy-3,7-dimethoxyflavone(4),diosmetin(5),3,3’,4’,5-tetrahydroxy-7-methoxyflavone(6),3,5-dihydroxy-3’,4’,7-trimethoxyflavone(7),chrysosplenol C(8),3,3’,5-trihydroxy-4’,7-dimethoxyflavanone(9),blumeatin(10),3,3’,5,7-tetrahydroxy-4’-methoxyflavanone(11),3’,5,5’,7-tetrahydroxyflavanone(12).Conclusion: Among them,compounds 1,3-5 and 8 were isolated from the genus Blumea for the first time,and compounds 6,7 were isolated from B.balsamifera for the first time.