射频消融与手术切除治疗小肝癌的Meta分析

目的：比较经皮射频消融与手术切除治疗小肝癌的疗效。方法：计算机检索文献,对纳入研究的方法及质量进行评价,并用RevMan 4.2.10版软件进行统计分析。结果：共纳入9个随机对照研究,Meta分析结果表明,两种治疗方法的1年总生存率差异无统计学意义,1、3年无瘤生存率、1年复发率手术组占优势。术后主要并发症及总住院时间,经皮射频消融组要优于手术组,差异有统计学意义（P〈0.05）。结论：经皮热射频消融治疗小肝癌短期内总体疗效差异不大,但是远期看来,手术组的生存率较高,复发率要低于射频组。

Radiofrequency ablation versus surgical resection for the treatment of hepatocellular carcinoma-a meta analysis

Objective:To compare the effectiveness of percutaneous radiofrequency ablation(RFA)and surgical resection(RC) as an initial treatment for patients with small hepatocellular carcinoma(HCC).Methods:The relevant literature was selected by computer.Statistical analysis of data rely on the software of RevMan 4.2.10.Results:The results included 9 randomized controlled studies.Targeting the tumor diameter less than or equal to 5 cm of small hepatocellular carcinoma.Conclusions:The difference of short-term percutaneous radiofrequency in the treatment of small hepatocellular carcinoma total curative effect is not notable,but from the long-term view,operation group,the survival rate and recurrence rate are dominant.