| 抑郁障碍患者丘脑-垂体-肾上腺轴释放功能与病情关系的研究 |
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| 引用本文： | 李宏伟,高镇松,吴强,黄佩珊,林春湖,陈耿谊. 抑郁障碍患者丘脑-垂体-肾上腺轴释放功能与病情关系的研究[J]. 黑龙江医学, 2011, 35(11): 808-810,855. DOI: 10.3969/j.issn.1004-5775.2011.11.003 |
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| 作者姓名： | 李宏伟 高镇松 吴强 黄佩珊 林春湖 陈耿谊 |
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| 作者单位： | 广东省汕头市第四人民医院,广东,汕头,515021 |
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| 基金项目： | 广东省医学科研基金项目(A2009648) |
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| 摘 要： | 目的 探讨抑郁障碍患者下丘脑-垂体-肾上腺(HPA)轴释放功能与病情的关系.方法 对50例抑郁障碍患者以电化学发光法测定血浆皮质醇和昼夜分泌节律,同步测定24 h尿17-羟皮质醇、24 h尿游离皮质酮、地塞米松抑制试验(DST),评估其下丘脑-垂体-肾上腺(HPA)轴的释放功能,同时以汉密顿抑郁量表(HAMD-17)、...
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| 关 键 词： | 抑郁障碍 下丘脑-垂体-肾上腺轴 皮质醇 神经内分泌 |
A Correlated Study on Release Fuction of Hypothalamus-pituitary-adrenal(HPA) Axis and the Ill-conditions in Patients with Depression Disorder |
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| LI Hong-wei,GAO Zhen-song,WU Qiang,et al.. A Correlated Study on Release Fuction of Hypothalamus-pituitary-adrenal(HPA) Axis and the Ill-conditions in Patients with Depression Disorder[J]. Heilongjiang Medical Journal, 2011, 35(11): 808-810,855. DOI: 10.3969/j.issn.1004-5775.2011.11.003 |
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| Authors: | LI Hong-wei GAO Zhen-song WU Qiang et al. |
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| Affiliation: | LI Hong-wei,GAO Zhen-song,WU Qiang,et al.(Department of Psychiatry,the Fourth People′s Hospital of Shantou City of Guangdong Province, Shantou 515021,CHINA) |
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| Abstract: | Objective To explore the correlation between the release function of hypothalamus-pituitary-adrenal(HPA) axis and the ill-conditions in patients with depression disorder.Methods Using electrochemistry luminescence,totally 50 cases with depression disorder were tested plasma cortisol and morning-night secretion rhythm,and,24 h urine 17-OH cortisol and 24 h urine free corticosterone,dexamethasone suppression test(DST),so as to evaluate the release function of hypothalamus-pituitary-adrenal(HPA) axis.At the sa... |
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| Keywords: | Depression disorder Hypothalamus-pituitary-adrenal(HPA)axis Cortisol Neurocrine |
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