| 急性脑梗塞患者脑脊液催产素和生长抑素含量的变化 |
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| 引用本文： | 刘新峰,史荫绵,金泳清.急性脑梗塞患者脑脊液催产素和生长抑素含量的变化[J].医学研究生学报,1992(2). |
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| 作者姓名： | 刘新峰 史荫绵 金泳清 |
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| 作者单位： | 金陵医院神经内科，第二军医大学长海医院神经科，金陵医院神经内科 |
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| 摘 要： | 本文应用放射免疫分析法对30例急性脑梗塞患者脑脊液(CSF)中催产素(OT)和生长抑素(SS)含量的变化进行了观察。结果表明,脑梗塞患者 CSF 中 OT,SS 含量均显著高于对照组,且脑梗塞病情重者 OT 含量明显高于轻者.头颅 CT 示脑梗塞体积大者 OT 和 SS 含量又显著高于体积小者。结果提示,OT 和 SS 可能参与急性缺血性脑损伤的病理生理过程,故测定 CSF 中 OT 和 SS 含量可反映缺血性脑损伤的严重程度,以及时指导临床治疗.
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| 关 键 词： | 脑梗塞 催产素 生长抑素 放射免疫分析 |
An observation on oxytocin and somatostatin levels of cerebrospinal fluid in patients with acute cerebral infarction |
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| Liu Xinfeng.An observation on oxytocin and somatostatin levels of cerebrospinal fluid in patients with acute cerebral infarction[J].Bulletin of Medical Postgraduate,1992(2). |
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| Authors: | Liu Xinfeng |
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| Institution: | Department of Neurology |
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| Abstract: | The contents of oxytocin (OT) and somatostatin (SS) in cerebrospinal fluid (CSF) were determined by radioimmunoassy in 30 pati- ents with acute cerebral infarction.The results showed that the OT and SS of CSF were significantly increased as compared with the control.The OT contents of CSF were much higher in severe cases than that of mild cases, and the contents of SS and OT in the large volume of the cerebral infarc- tion demonstrated by CT scanning were also higher than that in the small volume of the infarction.These suggested that SS and OT might be involved in the pathophysiological process of acute ischemic brain damage.The chan- ges of SS and OT in CSF could reflect the serious degree of the brain da- mage.And its mechanism must be reserched in further. |
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| Keywords: | cerebral infarction oxytocin somatostatin radioimmunoassy |
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