Oral transmucosal ketamine: an effective premedication in children |
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Authors: | RUXANDRA CIOAC ,& ION CANAVEA |
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Affiliation: | Department of Anaesthesiology, Oral and Maxillo-facial Surgery, University of Medicine, Bucharest, Romania |
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Abstract: | The oral cavity offers a simple, painless way of drug administration. For this reason, we used oral transmucosal ketamine (5–6 mg·kg−1) for premedication in 15 children and compared it with intranasal ketamine (5–6 mg·kg−1), placebo and intramuscular ketamine (5–6 mg·kg−1). Oral transmucosal ketamine (OTK) provided effective sedation, facilitated i.v. line insertion and was accepted with pleasure by the patients (as lollipops). The lollipops produced a slight increase in gastric volumes but did not affect gastric pH. In conclusion OTK has been shown to be an effective, harmless preoperative medication in paediatric patients. |
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