骨矿物质含量测定对早产儿代谢性骨病的诊断价值

评价骨矿物质含量（骨矿含量）测定对早产儿代谢性骨病（ｍｅｔａｂｏｌｉｃｂｏｎｅｄｉｓｅａｓｅｏｆｐｒｅｍａｔｕｒｉｔｙ，ＭＢＤＰ）的诊断价值。方法用单光子吸收法（ＳＰＡ）检测３８例日龄大于３周早产儿骨矿含量，同时作右前臂Ｘ线检查，并与５５例健康早产儿进行比较。结果８例早产儿骨线密度（ＢＭＣ）、骨面密度（ＢＭＤ）明显降低，其中４例Ｘ线检查有骨质疏松和（或）佝偻病样表现，提示ＭＢＤＰ，其余３０例骨矿含量正常者Ｘ线检查均未见异常。结论骨矿含量测定对ＭＢＤＰ早期诊断有一定价值。

THE SIGNIFICANCE OF BONE MINERAL ANALYSIS IN THE DIAGNOSIS OF METABOLIC BONE DISEASE OF PREMATURITY

PURPOSE To evaluate the signicance of bone mineral analyses in dignosing metabolic bone disease of prematurity (MBDP). METHODS Bone mineral content (MBC), bone mineral density (BMD) and bone width (BW) of the right radius were measured by single photon absorptiometry (SPA) in 38 preterm infants older than 3 weeks, compared with those in 55 cases of healthy preterm infants. At the same time, X-ray radiograph of the right forarm was taken. RESULTS The levels of BMC and BMD in 8 cases were less than 2 standard deviation (SD) of the mean of the same gestation age. Of the 8 cases, 4 appeared osteopenia or rickets radiographs which indicated MBDP. The other 30 patients all showed normal bone mineral concentration and radiographes . CONCLUSIONS The measurement of radial bone mineral content has an important clinical value in diagnosing MBDP early.