| 妇科疾患病变组织中癌抗原的分布及其意义 |
| |
| 引用本文： | 邹桂华,杨光娅.妇科疾患病变组织中癌抗原的分布及其意义[J].江西医学院学报,1994,34(4):29-31. |
| |
| 作者姓名： | 邹桂华 杨光娅 |
| |
| 作者单位： | 病理解剖学教研室，南昌330006 |
| |
| 摘 要： | 用抗小鼠宫颈癌单克隆抗体（Au14-1)对22种人妇科疾患（共46例）病理活检标本作辣根过氧化物酶抗辣根过氧化物酶法（PAP）染色，发现10例宫颈鳞状细胞癌中，8例阳性；2例阴性。6例不同类型的宫颈腺癌中4例为阳性，2例可疑；而宫内膜腺癌和慢性宫颈炎中的腺上皮及宫颈鳞癌中残余的正常腺体均为阴性，表明Au14-1可用于临床作为鉴别宫内膜腺癌与宫颈腺癌的一项较好的参考指标。
|
| 关 键 词： | 单克隆抗体 杂交瘤 子宫颈肿瘤 诊断 免疫组织化学 |
The Distribution and Significance of Carcinoma Antigen in Tissues of Gynecologie Diseases |
| |
| Zou Guihua,Yang Guangya.The Distribution and Significance of Carcinoma Antigen in Tissues of Gynecologie Diseases[J].Acta Academiae Medicinae Jiangxi,1994,34(4):29-31. |
| |
| Authors: | Zou Guihua Yang Guangya |
| |
| Abstract: | Using monoclonal antibodies to mouse utering cervical carcinoma,Au 14-1,twenty twokinds of human gynecological diseases( 46 cases)have been studied with PAP stainingmethod.8 of 10 cases of cervical squamous cell carcinomas were positive. All other kinds ofgynecologic squamous cell carcinom were negative. It was found that Au14-1 monoclonal an-tibody has higher specificity to human cervical squamous cell carcinomas. 4 of 6 cases of cer-vical adenocarcinoma were positive. 2 cases were doutful,But all adenocarcinomas of corpusuteri,epithelium of cervicitis and residual normal glands in cerical squamous carcinom werenegative. The results indicate that Au14-1 may be used as a favorable criterion for referencein distinguishing adenocarcinoma of corpus uteri from cervical adenocarcinoma. |
| |
| Keywords: | antibodies monoclonal byhridomas cervi neoplasms/diagnosis immunohistochemistry/methods |
| 本文献已被 CNKI 维普 等数据库收录！ |
