某地区老年人血8-羟基鸟嘌呤(8-OH-aG)水平调查 |
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引用本文: | 林春晓,马文军,文素娟,朱志良.某地区老年人血8-羟基鸟嘌呤(8-OH-aG)水平调查[J].中国热带医学,2009,9(6):1094-1095. |
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作者姓名: | 林春晓 马文军 文素娟 朱志良 |
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作者单位: | 1. 深圳市宝安区疾病预防控制中心,广东,深圳,518101 2. 北京大学公共卫生学院,北京,100191 3. 深圳市宝安区人民医院,广东,深圳,518101 |
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摘 要: | 目的测定某地区老年人血中8-羟基鸟嘌呤(8-OH—dG)水平,了解其在老年人群中的分布。方法用Human-8-OH-dG酶联免疫试剂盒检测血中8-OH-dG水平。结果正常人群中老年人血8-OH—dG水平为(11.43±7.53)ng/mg,男性为(11.39±7.21)ng/mg,女性为11.48-8.00ng/mg,不同性别间没有显著性差异。按60~69岁、70~79岁和对照组(50岁以下)3个年龄组分层,男性、女性和全体人群中各年龄组间血8—OH—dG水平无显著性差异(P〉0.05),但随着年龄增长血8-OH-dG水平有增高的趁势。结论该地区老年人血中8-羟基鸟嘌呤(8-OH—dG)水平男女性中位数分别为7.99ng/mg和7.38ng/mg;95%可信限其参考范围男性为0-28.68ng/mg,女性为0-27.83ng/mg。
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关 键 词: | 8-羟基鸟嘌呤(8-OH-dG) 老年人 参考值范围 |
Survey of blood 8-OH-dG level in the elderly in China |
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Institution: | LIN Chun-xiao, MA Wen-jun, WEN Su-juan, et al. ( 1. Baoan District Center for Disease Control and Prevention, Shenzhen 518101, Guangdong, P. R. China ) |
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Abstract: | Objective To detect the level of 8-OH--riG in blood of the elderly. Methods The content of blood 8- OH-dG were determined by ELISA kits. Results The average level of blood 8-OH-dG of normal senile population was (11.43±7.53)ng/mg.There was no significant difference between males and females, and the levels were (11.39±7.21 )ng/mg and 11.48±8.00ng/mg respectively. The level of blood 8-OH-dG showed increasing trend along with the increase of the age. Conclusions The median value of blood 8-OH-dG of elderly males and females were 7.99ng/mg and 7.38ng/mg. |
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Keywords: | 8-OH--dG The elderly Reference range |
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