山西省职业暴露人群高致病性禽流感(H5N1)血清抗体水平调查

目的了解山西省职业暴露人群高致病性禽流感(H5N1)感染现状,探索高危人群的暴露情况与感染途径,为防控工作提供依据。方法现场问卷调查职业暴露人群,用单放射免疫扩散溶血实验检测高致病性禽流感(H5N1)的血清抗体水平。结果山西省的职业暴露人群以青壮年为主;主要暴露方式以加工(44.93%)、喂养+清扫禽舍(21.74%)和喂养+清扫禽舍+捕捉(15.94%)为主;接触病死禽时91.89%的人员采取了防护措施;研究显示山西职业暴露人群H5N1病毒的感染率为0.97%,曾经发生过高致病性禽流感疫情的县与未发生过疫情的县感染率差异无统计学意义(χ2=0.000,P=0.995)。结论山西省禽类职业暴露人群可能存在H5N1隐性感染,并提示无论是否发生过禽间疫情,均需加强监测与管理。

Detection of antibody against high pathogenic avian influenza (H5N1) virus in occupational exposed population in Shanxi

Objective To learn the current status of H5N1 infection in the population of occupationally exposed to the virus in Shanxi,and to address the relationship between the occupational exposure and virus infection.Methods A total of 207 workers were investigated.Serum antibody against H5N1 was detected using Single Radial Hemolytic Technique(SRH) method.Results The majority of occupational population exposed to H5N1 virus was young adult.Workers involved in processing(44.93%),feeding and cleaning(21.74%) plus capturing(15.94%) were more likely to get infected,although 91.89% participants have indeed taken protective measures after dealing with sick or dead birds.Our study also showed that the overall infection rate in this population was 0.97%,with no significant difference between the two counties with /without H1N1epidemic(χ2=0.000,P=0.995).Conclusions There is a possibility of latent infection among people who occupationally exposed to H5N1 virus.Also this study suggested that,strict surveillance and management are necessary in all the areas regardless their epidemic status.