新疆地区汉族和维吾尔族健康人群前臂骨密度测量结果及差异性分析

目的通过测量新疆地区3264例汉族、维吾尔族健康人群前臂骨密度(Bone mineral density,BMD),建立本地区双能X线骨密度仪(Duel energy X-ray absorptiometer,DXA))测量前臂骨密度的正常数据库,比较两族BMD随年龄变化的规律,评价两族骨质疏松(Osteoporosis,OP)发病率之间的差异。方法使用法国DMS公司生产的Lexxos型DXA对新疆地区汉族和维吾尔族20岁以上健康人群前臂BMD进行测量,按不同性别每5岁分为1年龄组,得出骨密度均值、标准差和骨质疏松发生率。结果①汉族男性骨峰值见于30～34岁,女性骨峰值40～44岁;维吾尔族男性骨峰值40～44岁,女性骨峰值25～29岁,维吾尔族男、女峰值骨量分别高于汉族男、女峰值骨量。②同一族别中相同年龄段同一测定区域BMD男性均高于女性;两族同性别BMD(男性在20～24岁、25～29岁、40～44岁3个年龄段和女性在20～24岁、25～29岁两个年龄段)存在统计学差异(P<0.05)。③两族男女OP发生率之间均没有统计学差异(P>0.05)。结论不同族别、不同性别到达骨峰值的年龄不同,骨量峰值水平也不同,本研究提供了新疆地区汉族和维吾尔族DXA测量前臂各年龄段BMD的参考数据和OP发生率,为国内的资料比较提供了依据。

Investigation results and variation analysis of forearm bone mineral density in healthy Han and Uygur people in Xinjiang

Objective To establish the normal database of forearm bone mineral density(BMD) measured with dual-energy X-ray absorptiometer(DXA) through measuring forearm BMD of 3264 healthy Han and Uygur people in Xinjiang,to compare the variation rules of BMD along with ages in two ethnic groups,and to evaluate the difference of incidence of osteoporosis between Han and Uygur groups.Methods Forearm BMD of healthy Han and Uygur people over 20 years old were measured using DXA detector(Model lexxos made by DMS co.Ltd,France).All subjects were divided into different groups according to the gender and age(by 5 years).Mean BMD,standard deviation(SD),and incidence of osteoporosis were acquired.Results(1) The peak value of bone mass in Han males and females happened in the 30～34 years old group and 40～44 years old group,respectively.The peak value of bone mass in Uighur males and females happened in the 40～44 years old group and 25～29 years old group,respectively.The peak value of bone mass in Uighur people was higher than that in Han people.(2) The mean BMD of males was higher than that of females in the same age,area,and ethnics.The mean BMD(males 20～24,25～29,40～44 in three ages and females 20～24,25～29 in two ages) of the same gender in Han and Uygur ethnic group was significantly different(P<0.05).(3) There was no statistically significant difference between incidence of osteoporosis in Han and Uygur groups(P>0.05).Conclusion The peak value of bone mass in different ethnics and genders appears at different ages and the level of results is also different.This study may provide reference data for forearm BMD measured with DXA and incidence of osteoporosis in Han and Uygur ethnic groups in Xinjiang,and provide a basis for comparison of domestic information.