老年结直肠癌腹腔镜辅助与开腹根治术的近期和远期疗效比较

目的比较老年结直肠癌腹腔镜辅助与开腹根治术的近期和远期疗效。 方法回顾性分析2013年1月至2015年1月58例年龄≥70岁老年结直肠癌患者的临床资料,根据手术方式分为腹腔镜组(27例)和开腹组(31例),采用SPSS20.0软件进行统计学分析,围手术期相关指标等以( ±s)表示,独立样本t检验;术后并发症发生率、局部复发率、远处转移率和累积生存率等组间比较采用χ²检验,生存率比较用Kaplan－Meier检验,均以P<0.05为差异有统计学意义。 结果两组患者手术时间、淋巴结清扫数目比较,差异均无统计学意义(P>0.05)。腹腔镜组术中出血量、VSA评分、术后首次通气时间、恢复饮食时间以及平均住院时间均明显优于开腹组(P<0.05);两组患者术后并发症发生率、局部复发率、远处转移率和累积生存率比较,差异均无统计学意义(P>0.05)。 结论腹腔镜辅助治疗老年结直肠癌是安全可行的,值得在临床中进一步推广应用。

The comparison of short-term and long-term therapeutic effect of laparoscopic-assisted surgery versus open surgery for the elderly patients with colorectal cancer

ObjectiveTo compare the short-term and long-term therapeutic effect of laparoscopic-assisted surgery versus open surgery for the elderly patients with colorectal cancer. MethodsFrom January 2013 to January 2015, a retrospective analysis was performed in 58 elderly patients (aged≥70) with colorectal cancer, including 27 cases in laparoscopy group and 31 cases in laparotomy group. Statistical analysis were performed by using SPSS20.0 software, perioperative related indicators were expressed as mean±standard deviation and were examined by using t test. Post-operative complication rate, local recurrence rate, distal metastasis rate and accumulative survival rate were examined by using Chi-square test. The survival rate was examined by using Kaplan-Meier test. A P<0.05 was considered as statistically significant difference. ResultsThere were no significant differences between the two groups in terms of operation time and number of lymph nodes (P>0.05). The intraoperative blood loss, VAS score, first flatus time, diet recovery time and the average hospitalization time in laparoscopy group were significantly better than those in the laparotomy group (P<0.05), there were no significant differences between the two groups in terms of post-operative complication rate, local recurrence rate, distal metastasis rate and accumulative survival rate (P>0.05). ConclusionLaparoscopic-assisted surgery in treating the elderly patients with colorectal cancer is feasible and safe, which is valuable to be applied in clinic.