| Abstract: | Hypoxic hepatitis (HH), also known as ischemic hepatitis or shock liver, is a liver injury characterized by necrosis of centrilobular hepatocytes with a rapid increase in serum aminotransferase levels. The incidence rate of HH among patients in the intensive care unit (ICU) was found to be 0.9%-11.9% [1]. Occurrence of HH appears to have a significant impact on the clinical outcome. The 30-day mortality rate in critically ill patients who developed HH has been reported to be over 50% [1,2]. Nevertheless, raised aminotransferase levels are still not given sufficient consideration in the clinical context. The high incidence and the strong prognostic impact of HH on ICU survival encourage research to recognize its occurrence as early as possible [3]. |
