癌症复发恐惧量表汉化及信效度初测

目的汉化英文版癌症复发恐惧量表(FCRQ)及初步分析其在评估癌症患者复发恐惧心理中的信效度。 方法经过量表翻译、回译、专家小组评议调适后形成癌症复发恐惧量表初步汉化版。采取回顾性分析2018年1月至2018年12月在南方医科大学南方医院、广东省人民医院及广州市妇女儿童医疗中心肿瘤中心收治的571例癌症病例资料，其中男性52例，女性519例；年龄21～88岁，平均(47.50±11.43)岁。使用癌症复发恐惧量表(FCRQ)、恐惧疾病进展简化量表(FoP-Q-SF)、抑郁症筛查量表(PHQ-9)与焦虑症筛查量表(GAD-7)进行评估，同时收集患者社会人口学资料。一个月后采用随机数表法简单随机抽取50%(285名)患者进行复测，计算量表复测信度。 结果量表克朗巴哈系数(Cronbach’s alpha)为0.86，Spearman Brown分半信度为0.89，重测信度为0.90。探索性因子分析显示量表为单因子结构，可解释总变异65.91%。量表各条目与总分的相关系数为0.575～0.874。除条目6外(因子载荷0.577)，其余条目在主成分载荷为0.787～0.894。汉化版FCRQ量表与FoP-Q-SF、PHQ9与GAD7均呈正相关(相关系数0.524～0.758，P<0.05)。 结论汉化版癌症复发恐惧量表具有良好的信效度，可以作为国内开展相关领域研究的临床评估工具。

Chinese version of fear of cancer recurrence questionnaire for cancer patients: a preliminary study

ObjectiveTo translate the English version of the Fear of Cancer Recurrence Questionnaire(FCRQ)into Chinese and to test its validity and reliability among Chinese cancer patients. MethodsAfter we achieved a draft Chinese version, we recruited 571 cancer patients (52 males and 519 females, mean age: 47.50±11.43 years, range from 21 to 88 years) from Southern Medical University Nanfang Hospital, Guangdong Provincial People’s Hospital and Guangzhou Women and Children’s Medical Center and asked them to complete the FCRQ, the Fear of Progression Questionnaire – Short Form(FoP-Q-SF), the Patient Health Questionnaire(PHQ-9) and the General Anxiety Disorder Questionnaire(GAD-7). Cronbach’s alpha was calculated and Explorary Factorial Analysis(EFA)was conducted. Fifty percent of the participants were randomly selected and re-contacted after one month to explore the test-retest reliability. ResultsThe Cronbach’s alpha of the Chinese FCRQ scale was 0.86, Spearman Brown coefficient was 0.89, and the test-retest coefficient was 0.90. EFA revealed that the scale was a single factor instrument, and it explained up to 65.91% of the total variance. The r value between scale item and total score ranged from 0.575 to 0.876, and their loadings showed satisfactory outcomes (ranged from 0.787 to 0.894)except for item 6(loading=0.577). The FCRQ showed significant correlation with FoP-Q-SF, PHQ9 and GAD7 scales(r values ranged from 0.524-0.758). ConclusionThe Chinese version FCRQ is reliable and could be utilized in the field of cancer research.