旁正中矢状断层上大脑距状沟立体定位数据集的构建及差异性分析

目的构建大脑半球旁正中矢状断层上（X=±7 mm）距状沟的立体定位数据集，探讨距状沟是否具有侧别、性别和位置差异性。方法以连合间径中点为原点建立三维立体坐标系，30名健康成人大脑旁正中矢状断层T1MRI上，3D-Doctor软件测量距状沟沟长，该断层上Y值为3 mm的倍数处选取测量点构建数据集，求Z值对Y值的二次曲线回归方程。结果旁正中矢状断层上距状沟沟长不具有侧别和性别差异（P>0.05），Y轴方向上距状沟后端左侧较右侧位置偏后（P < 0.05）。旁正中矢状断层上距状沟呈现距离大脑原点越近位置变异性越小的规律，旁正中矢状断层上距状沟Z值对Y值的二次曲线回归方程:左侧Z=-32.717-1.587Y-0.016Y2（P < 0.01），右侧Z=-30.390-1.537Y-0.015Y2（P < 0.01）。结论构建的距状沟立体定位数据集预期对该沟附近的视皮质功能区定位、病灶定位及外科治疗具有指导意义。

The building of the stereotactic data set of calcarine sulcus and difference analysis of the paramedian sagittal plane

ObjectiveTo build the stereotactic data set of calcarine sulcus(CS) on the paramedian sagittal plane(X=±7 mm), and explore the CS variability among different lateral, gender and position.MethodsThe three-dimensional coordinate system was established with the midpoint of AC-PC line as the origin.The length of CS on paramedian sagittal T1MRI planes of the brain of 30 healthy adults were measured using 3D-Doctor workstation, the measurement points were selected at a multiple of 3 mm on this section to construct the data set, and the quadratic regression equation of Z value to Y value was calculated.ResultsThe differences of the length of CS in different laterals and genders were not statistically significant(P>0.05).In the direction of Y axis, the left side of the back end of the CS was behind the right side.On paramedian sagittal planes, the smaller the positional variability of CS was, the closer the CS to the origin of the brain was.On paramedian sagittal plane, the quadratic regression equations of Z-value to Y-value of the CS in the left side and right side were Z=-32.717-1.587Y-0.016Y2 and Z=-30.390-1.537Y-0.015Y2, respectively(P < 0.01).ConclusionsThe building stereotaxic data set in this study is expected to be of guiding significance for the localizating the visual cortical functional areas, lesion area and surgical treatment in the vicinity of the calcarine sulcus.