颅内动脉狭窄数目与脑梗死严重程度的相关性研究

目的探讨颅内动脉狭窄数目与脑梗死的病情严重程度的相关性。方法回顾性分析100例经头颅磁共振确诊的脑梗死病人；脑梗死的临床症状严重程度采用美国国立卫生研究院卒中量表（NIHSS评分量表）衡量；颅内狭窄的血管采用颈部MRA评估，统计双侧的颈内动脉和椎动脉狭窄血管的数目，分析颅内动脉狭窄数目与NIHSS评分之间的关系。结果年龄、颅内动脉狭窄数目及空腹血糖为脑梗死病情严重程度的危险因素（P < 0.05~P < 0.01）；不同颅内动脉狭窄的数目NIHSS评分差异有统计学意义（P < 0.01），单支低于多支（P < 0.01），单支和双支、双支和多支NIHSS评分差异无统计学意义（P>0.05）。结论颅内动脉狭窄数目与脑梗死病情的严重程度显著相关，且为脑梗死病情的严重程度的独立危险因素。

Study on the correlation between the number of intracranial artery stenosis and severity of cerebral infarction

ObjectiveTo investigate the correlation between the number of intracranial artery stenosis and severity of cerebral infarction.MethodsThe clinical data of 100 patients with acute cerebral infarction were retrospectively analyzed.The clinical symptom severity and vascular stenosis of patients were evaluated using the national institutes of health stroke scale(NIHSS) and cervical MRA, respectively.The number of bilateral internal carotid artery and vertebral artery stenosis were counted, and the correlation between the number of intracranial artery stenosis and NIHSS score was analyzed.ResultsThe age, number of intracranial artery stenosis and fasting blood glucose were the risk factors of the severity of ischemic stroke(P < 0.05 to P < 0.01).The difference of the NIHSS score in patients with different number of intracranial artery stenosis was statistically significant(P < 0.01), and which in patients with single branch stenosis was lower than that in patients with multiple branches stenosis(P < 0.01), and the differences of the NIHSS score between single and double branches, and between double and multiple branches were not statistically significant(P>0.05).ConclusionsThe number of intracranial artery stenosis is significantly related to the severity of cerebral infarction, and the independent risk factor of the severity of cerebral infarction.