大脑额下沟断层解剖学相关性研究

目的探讨健康右利手成人额下沟的形态学特征及其侧别差异与性别差异，为Broca区功能研究提供解剖学参考。方法对40名健康右利手成人头颅MRI的横断面、冠状面及矢状面断层图像的80侧额下沟进行统计分析，研究额下沟的侧别差异及性别差异。结果不同性别情况下，额下沟在横断面出现层数差异无统计学意义（P>0.05）。女性右侧额下沟Y值均大于左侧，但除Z=18 mm层面外（P < 0.01），各层面左右侧Y值差异均无统计学意义（P>0.05）。男性左、右侧额下沟X值均大于女性，在右侧Z=2~10 mm、14~16 mm、20~26 mm层面，左侧Z=2 mm、10~16 mm、24~30 mm层面，男女X值差异均有统计学意义（P < 0.05~P < 0.01）。在左侧Z=18~20 mm和Z=24 mm层面，男性额下沟Y值均大于女性（P < 0.01），其他各层面男女性左侧Y值差异均无统计学意义（P>0.05）。结论额下沟在越靠近大脑中轴处，后天发育变异度越小，额下沟在前后方向及左右方向变异度大。

Correlative study on the sectional anatomy of inferior frontal sulcus in human brain

ObjectiveTo explore the morphological characteristics, bilateral and gender differences of the inferior frontal sulcus(IFS) in right-handed healthy adults, and provide the anatomical reference for the function study of Broca's area.MethodsThe transverse, coronal and sagittal planes of MRI images of 80 unilateral IFS in 40 right-handed healthy adults brain were statistically analyzed, and which was used to investigate the bilateral and gender differences.ResultsThe difference of the transverse layer number of IFS between two genders was not statistically significant(P>0.05).The Y value of right IFS was greater than that of left IFS in female, and the differences of the right Y value among other layers except for Z=18 mm layer were not statistically significant(P>0.05).The X value of left and right IFS in male was greater than that in female, and the differences of the X value at Z=2-10 mm, 14-16 mm and 20-26 mm layers of right IFS, and Z=2 mm, 10-16 mm and 24-30 mm layers of left IFS between male and female were statistically significant(P < 0.05 to P < 0.01).At Z=18-20 mm and Z=24 mm layers of left IFS, the Y value in male was greater than that in female(P < 0.01), and the differences of the Y value of other layers of left IFS between female and male were not statistically significant(P>0.05).ConclusionsThe closer to the brain middle axis the IFS, the smaller the acquired developmental variability of IFS is, and the larger the variabilities of IFS at the direction of forward-backward and left-right are.